| 1 | Sat 10 Aug | 42-3 v WrexhamWrexham 3-2 Wycombe Wanderers | Sky Bet League One |
| 2 | Tue 13 Aug | 42-0 v Northampton TownNorthampton Town 0-2 Wycombe Wanderers | Carabao Cup First Round |
| 3 | Sat 17 Aug | 4 2-3 v Birmingham CityWycombe Wanderers 2-3 Birmingham City | Sky Bet League One |
| 4 | Sat 24 Aug | 4 2-0 v Rotherham UnitedWycombe Wanderers 2-0 Rotherham United | Sky Bet League One |
| 5 | Wed 28 Aug | 41-0 v Swansea CitySwansea City 0-1 Wycombe Wanderers | Carabao Cup Second Round |
| 6 | Sat 31 Aug | 42-2 v BlackpoolBlackpool 2-2 Wycombe Wanderers | Sky Bet League One |
| 7 | Sat 14 Sep | 4 2-1 v Northampton TownNorthampton Town 1-2 Wycombe Wanderers | Sky Bet League One |
| 8 | Sat 21 Sep | 4 2-1 v Cambridge UnitedWycombe Wanderers 2-1 Cambridge United | Sky Bet League One |
| 9 | Tue 24 Sep | 41-2 v Aston VillaWycombe Wanderers 1-2 Aston Villa | Carabao Cup Third Round |
| 10 | Sat 28 Sep | 42-1 v Bristol RoversBristol Rovers 1-2 Wycombe Wanderers | Sky Bet League One |
| 11 | Tue 1 Oct | 42-2 v BarnsleyBarnsley 2-2 Wycombe Wanderers | Sky Bet League One |
| 12 | Sat 5 Oct | 41-0 v Crawley TownWycombe Wanderers 1-0 Crawley Town | Sky Bet League One |
| 13 | Sat 19 Oct | 43-1 v Peterborough UnitedWycombe Wanderers 3-1 Peterborough United | Sky Bet League One |
| 14 | Tue 22 Oct | 4 3-2 v Burton AlbionBurton Albion 2-3 Wycombe Wanderers | Sky Bet League One |
| 15 | Sat 2 Nov | 43-2 v York CityWycombe Wanderers 3-2 York City | Emirates FA Cup First Round |
| 16 | Tue 5 Nov | 45-0 v Stockport CountyStockport County 0-5 Wycombe Wanderers | Sky Bet League One |
| 17 | Sat 9 Nov | 4 1-0 v Wigan AthleticWigan Athletic 0-1 Wycombe Wanderers | Sky Bet League One |
| 18 | Tue 12 Nov | 42-1 v Crawley TownWycombe Wanderers 2-1 Crawley Town | EFL Trophy Southern Group B |
| 19 | Thu 26 Dec | 43-0 v StevenageStevenage 0-3 Wycombe Wanderers | Sky Bet League One |
| 20 | Sun 29 Dec | 41-2 v Charlton AthleticCharlton Athletic 2-1 Wycombe Wanderers | Sky Bet League One |
| 21 | Wed 1 Jan | 42-1 v Exeter CityWycombe Wanderers 2-1 Exeter City | Sky Bet League One |
| 22 | Sat 4 Jan | 4 1-1 v BlackpoolWycombe Wanderers 1-1 Blackpool | Sky Bet League One |
| 23 | Tue 7 Jan | 40-1 v Huddersfield TownWycombe Wanderers 0-1 Huddersfield Town | Sky Bet League One |
| 24 | Fri 10 Jan | 42-0 v PortsmouthWycombe Wanderers 2-0 Portsmouth | Emirates FA Cup Third Round |
| 25 | Sat 18 Jan | 42-1 v Mansfield TownMansfield Town 1-2 Wycombe Wanderers | Sky Bet League One |
| 26 | Sat 25 Jan | 40-0 v Northampton TownWycombe Wanderers 0-0 Northampton Town | Sky Bet League One |
| 27 | Tue 28 Jan | 42-1 v BarnsleyWycombe Wanderers 2-1 Barnsley | Sky Bet League One |
| 28 | Sat 1 Feb | 41-1 v Cambridge UnitedCambridge United 1-1 Wycombe Wanderers | Sky Bet League One |
| 29 | Sat 8 Feb | 40-0 v Preston North EndPreston North End 0-0 Wycombe Wanderers | Emirates FA Cup Fourth Round |
| 30 | Sat 15 Feb | 41-1 v Crawley TownCrawley Town 1-1 Wycombe Wanderers | Sky Bet League One |
| 31 | Tue 18 Feb | 42-0 v Bristol RoversWycombe Wanderers 2-0 Bristol Rovers | Sky Bet League One |
| 32 | Sat 22 Feb | 40-0 v Wigan AthleticWycombe Wanderers 0-0 Wigan Athletic | Sky Bet League One |
| 33 | Sat 1 Mar | 40-1 v Birmingham CityBirmingham City 1-0 Wycombe Wanderers | Sky Bet League One |
| 34 | Tue 4 Mar | 42-0 v Burton AlbionWycombe Wanderers 2-0 Burton Albion | Sky Bet League One |
| 35 | Sat 8 Mar | 41-1 v Peterborough UnitedPeterborough United 1-1 Wycombe Wanderers | Sky Bet League One |
| 36 | Sat 15 Mar | 40-1 v WrexhamWycombe Wanderers 0-1 Wrexham | Sky Bet League One |
| 37 | Tue 18 Mar | 43-2 v Rotherham UnitedRotherham United 2-3 Wycombe Wanderers | Sky Bet League One |
| 38 | Sat 29 Mar | 41-0 v Lincoln CityWycombe Wanderers 1-0 Lincoln City | Sky Bet League One |
| 39 | Tue 1 Apr | 40-0 v Shrewsbury TownWycombe Wanderers 0-0 Shrewsbury Town | Sky Bet League One |
| 40 | Sat 5 Apr | 40-1 v ReadingReading 1-0 Wycombe Wanderers | Sky Bet League One |
| 41 | Tue 8 Apr | 41-0 v Huddersfield TownHuddersfield Town 0-1 Wycombe Wanderers | Sky Bet League One |
| 42 | Sat 12 Apr | 41-0 v StevenageWycombe Wanderers 1-0 Stevenage | Sky Bet League One |
| 43 | Fri 18 Apr | 42-0 v Bolton WanderersBolton Wanderers 0-2 Wycombe Wanderers | Sky Bet League One |
| 44 | Mon 21 Apr | 40-4 v Charlton AthleticWycombe Wanderers 0-4 Charlton Athletic | Sky Bet League One |
| 45 | Sat 26 Apr | 40-1 v Leyton OrientLeyton Orient 1-0 Wycombe Wanderers | Sky Bet League One |
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