| 1 | Tue 21 Sep 2021 | 41-6 v Manchester CityManchester City 6-1 Wycombe Wanderers | Carabao Cup Third Round |
| 2 | Tue 5 Oct 2021 | 41-2 v Milton Keynes DonsMilton Keynes Dons 2-1 Wycombe Wanderers | Papa John’s Trophy |
| 3 | Sat 16 Oct 2021 | 42-0 v Doncaster RoversDoncaster Rovers 0-2 Wycombe Wanderers | Sky Bet League One |
| 4 | Tue 19 Oct 2021 | 40-0 v Rotherham UnitedRotherham United 0-0 Wycombe Wanderers | Sky Bet League One |
| 5 | Sat 23 Oct 2021 | 42-1 v Crewe AlexandraWycombe Wanderers 2-1 Crewe Alexandra | Sky Bet League One |
| 6 | Tue 2 Nov 2021 | 41-4 v Ipswich TownWycombe Wanderers 1-4 Ipswich Town | Sky Bet League One |
| 7 | Sat 6 Nov 2021 | 42-2 v Hartlepool UnitedHartlepool United 2-2 Wycombe Wanderers | Emirates FA Cup First Round |
| 8 | Tue 22 Feb 2022 | 41-3 v Wigan AthleticWycombe Wanderers 1-3 Wigan Athletic | Sky Bet League One |
| 9 | Sat 26 Feb 2022 | 4 2-3 v Accrington StanleyAccrington Stanley 3-2 Wycombe Wanderers | Sky Bet League One |
| 10 | Fri 15 Apr 2022 | 42-0 v Plymouth ArgyleWycombe Wanderers 2-0 Plymouth Argyle | Sky Bet League One |
| 11 | Mon 18 Apr 2022 | 41-1 v AFC WimbledonAFC Wimbledon 1-1 Wycombe Wanderers | Sky Bet League One |
| 12 | Sat 23 Apr 2022 | 41-0 v Sheffield WednesdayWycombe Wanderers 1-0 Sheffield Wednesday | Sky Bet League One |
| 13 | Sat 30 Apr 2022 | 42-1 v Burton AlbionBurton Albion 1-2 Wycombe Wanderers | Sky Bet League One |
| 14 | Thu 5 May 2022 | 4 2-0 v Milton Keynes DonsWycombe Wanderers 2-0 Milton Keynes Dons | Sky Bet League One Play-off Semi Final |
| 15 | Sun 8 May 2022 | 40-1 v Milton Keynes DonsMilton Keynes Dons 1-0 Wycombe Wanderers | Sky Bet League One Play-off Semi Final |
| 16 | Sat 21 May 2022 | 40-2 v SunderlandSunderland 2-0 Wycombe Wanderers | Sky Bet League One Play-off Final |
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