| 1 | Sun 9 Aug 2015 | 52-0 v ArsenalArsenal 0-2 West Ham United | Barclays Premier League |
| 2 | Sat 22 Aug 2015 | 53-4 v AFC BournemouthWest Ham United 3-4 AFC Bournemouth | Barclays Premier League |
| 3 | Sat 29 Aug 2015 | 53-0 v LiverpoolLiverpool 0-3 West Ham United | Barclays Premier League |
| 4 | Mon 14 Sep 2015 | 52-0 v Newcastle UnitedWest Ham United 2-0 Newcastle United | Barclays Premier League |
| 5 | Sat 19 Sep 2015 | 52-1 v Manchester CityManchester City 1-2 West Ham United | Barclays Premier League |
| 6 | Tue 22 Sep 2015 | 51-2 v Leicester CityLeicester City 2-1 West Ham United | Capital One Cup Third Round |
| 7 | Sat 26 Sep 2015 | 52-2 v Norwich CityWest Ham United 2-2 Norwich City | Barclays Premier League |
| 8 | Sat 3 Oct 2015 | 22-2 v SunderlandSunderland 2-2 West Ham United | Barclays Premier League |
| 9 | Sat 17 Oct 2015 | 53-1 v Crystal PalaceCrystal Palace 1-3 West Ham United | Barclays Premier League |
| 10 | Sat 24 Oct 2015 | 52-1 v ChelseaWest Ham United 2-1 Chelsea | Barclays Premier League |
| 11 | Sat 31 Oct 2015 | 50-2 v WatfordWatford 2-0 West Ham United | Barclays Premier League |
| 12 | Sat 7 Nov 2015 | 51-1 v EvertonWest Ham United 1-1 Everton | Barclays Premier League |
| 13 | Sun 22 Nov 2015 | 51-4 v Tottenham HotspurTottenham Hotspur 4-1 West Ham United | Barclays Premier League |
| 14 | Sat 5 Dec 2015 | 50-0 v Manchester UnitedManchester United 0-0 West Ham United | Barclays Premier League |
| 15 | Sat 12 Dec 2015 | 50-0 v Stoke CityWest Ham United 0-0 Stoke City | Barclays Premier League |
| 16 | Sun 20 Dec 2015 | 50-0 v Swansea CitySwansea City 0-0 West Ham United | Barclays Premier League |
| 17 | Sat 26 Dec 2015 | 51-1 v Aston VillaAston Villa 1-1 West Ham United | Barclays Premier League |
| 18 | Mon 28 Dec 2015 | 52-1 v SouthamptonWest Ham United 2-1 Southampton | Barclays Premier League |
| 19 | Sat 2 Jan 2016 | 52-0 v LiverpoolWest Ham United 2-0 Liverpool | Barclays Premier League |
| 20 | Tue 12 Jan 2016 | 53-1 v AFC BournemouthAFC Bournemouth 1-3 West Ham United | Barclays Premier League |
| 21 | Sat 16 Jan 2016 | 51-2 v Newcastle UnitedNewcastle United 2-1 West Ham United | Barclays Premier League |
| 22 | Sat 30 Jan 2016 | 50-0 v LiverpoolLiverpool 0-0 West Ham United | Emirates FA Cup Fourth Round |
| 23 | Tue 2 Feb 2016 | 52-0 v Aston VillaWest Ham United 2-0 Aston Villa | Barclays Premier League |
| 24 | Sat 6 Feb 2016 | 50-1 v SouthamptonSouthampton 1-0 West Ham United | Barclays Premier League |
| 25 | Sat 9 Apr 2016 | 53-3 v ArsenalWest Ham United 3-3 Arsenal | Barclays Premier League |
| 26 | Wed 13 Apr 2016 | 51-2 v Manchester UnitedWest Ham United 1-2 Manchester United | Emirates FA Cup Quarter Final |
| 27 | Tue 10 May 2016 | 53-2 v Manchester UnitedWest Ham United 3-2 Manchester United | Barclays Premier League |
| 28 | Sun 15 May 2016 | 51-2 v Stoke CityStoke City 2-1 West Ham United | Barclays Premier League |
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