| 1 | Fri 6 Aug 2021 | 22-2 v AFC BournemouthAFC Bournemouth 2-2 West Bromwich Albion | Sky Bet Championship |
| 2 | Sat 14 Aug 2021 | 23-2 v Luton TownWest Bromwich Albion 3-2 Luton Town | Sky Bet Championship |
| 3 | Wed 18 Aug 2021 | 24-0 v Sheffield UnitedWest Bromwich Albion 4-0 Sheffield United | Sky Bet Championship |
| 4 | Sat 21 Aug 2021 | 2 2-1 v Blackburn RoversBlackburn Rovers 1-2 West Bromwich Albion | Sky Bet Championship |
| 5 | Sat 28 Aug 2021 | 2 1-0 v Peterborough UnitedPeterborough United 0-1 West Bromwich Albion | Sky Bet Championship |
| 6 | Sat 11 Sep 2021 | 21-1 v MillwallWest Bromwich Albion 1-1 Millwall | Sky Bet Championship |
| 7 | Tue 14 Sep 2021 | 20-0 v Derby CountyWest Bromwich Albion 0-0 Derby County | Sky Bet Championship |
| 8 | Sat 18 Sep 2021 | 21-1 v Preston North EndPreston North End 1-1 West Bromwich Albion | Sky Bet Championship |
| 9 | Fri 24 Sep 2021 | 22-1 v Queens Park RangersWest Bromwich Albion 2-1 Queens Park Rangers | Sky Bet Championship |
| 10 | Tue 28 Sep 2021 | 24-0 v Cardiff CityCardiff City 0-4 West Bromwich Albion | Sky Bet Championship |
| 11 | Fri 1 Oct 2021 | 20-1 v Stoke CityStoke City 1-0 West Bromwich Albion | Sky Bet Championship |
| 12 | Fri 15 Oct 2021 | 21-0 v Birmingham CityWest Bromwich Albion 1-0 Birmingham City | Sky Bet Championship |
| 13 | Wed 20 Oct 2021 | 2 1-2 v Swansea CitySwansea City 2-1 West Bromwich Albion | Sky Bet Championship |
| 14 | Sat 23 Oct 2021 | 23-0 v Bristol CityWest Bromwich Albion 3-0 Bristol City | Sky Bet Championship |
| 15 | Sat 30 Oct 2021 | 2 0-3 v FulhamFulham 3-0 West Bromwich Albion | Sky Bet Championship |
| 16 | Sat 6 Nov 2021 | 21-1 v MiddlesbroughWest Bromwich Albion 1-1 Middlesbrough | Sky Bet Championship |
| 17 | Sat 20 Nov 2021 | 20-1 v Huddersfield TownHuddersfield Town 1-0 West Bromwich Albion | Sky Bet Championship |
| 18 | Tue 23 Nov 2021 | 2 0-0 v BlackpoolBlackpool 0-0 West Bromwich Albion | Sky Bet Championship |
| 19 | Fri 26 Nov 2021 | 20-0 v Nottingham ForestWest Bromwich Albion 0-0 Nottingham Forest | Sky Bet Championship |
| 20 | Sat 4 Dec 2021 | 22-1 v Coventry CityCoventry City 1-2 West Bromwich Albion | Sky Bet Championship |
| 21 | Sat 11 Dec 2021 | 21-0 v ReadingWest Bromwich Albion 1-0 Reading | Sky Bet Championship |
| 22 | Fri 17 Dec 2021 | 20-0 v BarnsleyBarnsley 0-0 West Bromwich Albion | Sky Bet Championship |
| 23 | Mon 27 Dec 2021 | 20-1 v Derby CountyDerby County 1-0 West Bromwich Albion | Sky Bet Championship |
| 24 | Sat 8 Jan 2022 | 21-2 v Brighton & Hove AlbionWest Bromwich Albion 1-2 Brighton & Hove Albion | Emirates FA Cup Third Round |
| 25 | Sat 15 Jan 2022 | 20-1 v Queens Park RangersQueens Park Rangers 1-0 West Bromwich Albion | Sky Bet Championship |
| 26 | Sat 22 Jan 2022 | 23-0 v Peterborough UnitedWest Bromwich Albion 3-0 Peterborough United | Sky Bet Championship |
| 27 | Wed 26 Jan 2022 | 2 0-2 v Preston North EndWest Bromwich Albion 0-2 Preston North End | Sky Bet Championship |
| 28 | Sat 29 Jan 2022 | 2 0-2 v MillwallMillwall 2-0 West Bromwich Albion | Sky Bet Championship |
| 29 | Wed 9 Feb 2022 | 20-2 v Sheffield UnitedSheffield United 2-0 West Bromwich Albion | Sky Bet Championship |
| 30 | Mon 14 Feb 2022 | 20-0 v Blackburn RoversWest Bromwich Albion 0-0 Blackburn Rovers | Sky Bet Championship |
| 31 | Sat 19 Feb 2022 | 20-2 v Luton TownLuton Town 2-0 West Bromwich Albion | Sky Bet Championship |
| 32 | Tue 22 Feb 2022 | 2 1-2 v MiddlesbroughMiddlesbrough 2-1 West Bromwich Albion | Sky Bet Championship |
| 33 | Mon 28 Feb 2022 | 20-2 v Swansea CityWest Bromwich Albion 0-2 Swansea City | Sky Bet Championship |
| 34 | Sat 5 Mar 2022 | 22-0 v Hull CityHull City 0-2 West Bromwich Albion | Sky Bet Championship |
| 35 | Fri 11 Mar 2022 | 22-2 v Huddersfield TownWest Bromwich Albion 2-2 Huddersfield Town | Sky Bet Championship |
| 36 | Tue 15 Mar 2022 | 21-0 v FulhamWest Bromwich Albion 1-0 Fulham | Sky Bet Championship |
| 37 | Sat 19 Mar 2022 | 22-2 v Bristol CityBristol City 2-2 West Bromwich Albion | Sky Bet Championship |
| 38 | Sun 3 Apr 2022 | 20-1 v Birmingham CityBirmingham City 1-0 West Bromwich Albion | Sky Bet Championship |
| 39 | Wed 6 Apr 2022 | 2 2-0 v AFC BournemouthWest Bromwich Albion 2-0 AFC Bournemouth | Sky Bet Championship |
| 40 | Fri 15 Apr 2022 | 22-1 v BlackpoolWest Bromwich Albion 2-1 Blackpool | Sky Bet Championship |
| 41 | Mon 18 Apr 2022 | 2 0-4 v Nottingham ForestNottingham Forest 4-0 West Bromwich Albion | Sky Bet Championship |
| 42 | Sat 7 May 2022 | 24-0 v BarnsleyWest Bromwich Albion 4-0 Barnsley | Sky Bet Championship |
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