| 1 | Fri 25 Jul | 51-1 v Royal AntwerpRoyal Antwerp 1-1 Union Saint-Gilloise | Belgian Pro League |
| 2 | Sun 3 Aug | 55-0 v Oud-Heverlee LeuvenUnion Saint-Gilloise 5-0 Oud-Heverlee Leuven | Belgian Pro League |
| 3 | Sat 9 Aug | 53-2 v KAA GentKAA Gent 2-3 Union Saint-Gilloise | Belgian Pro League |
| 4 | Sat 16 Aug | 53-0 v Standard LiègeUnion Saint-Gilloise 3-0 Standard Liège | Belgian Pro League |
| 5 | Sun 24 Aug | 50-0 v La LouvièreLa Louvière 0-0 Union Saint-Gilloise | Belgian Pro League |
| 6 | Sat 13 Sep | 51-0 v FCV Dender EHFCV Dender EH 0-1 Union Saint-Gilloise | Belgian Pro League |
| 7 | Tue 16 Sep | 53-1 v PSV EindhovenPSV Eindhoven 1-3 Union Saint-Gilloise | UEFA Champions League Matchday 1 |
| 8 | Sun 21 Sep | 5 2-1 v KRC GenkKRC Genk 1-2 Union Saint-Gilloise | Belgian Pro League |
| 9 | Sat 27 Sep | 52-0 v KVC WesterloUnion Saint-Gilloise 2-0 KVC Westerlo | Belgian Pro League |
| 10 | Wed 1 Oct | 5 0-4 v Newcastle UnitedUnion Saint-Gilloise 0-4 Newcastle United | UEFA Champions League Matchday 2 |
| 11 | Sun 5 Oct | 5 0-1 v Club BruggeClub Brugge 1-0 Union Saint-Gilloise | Belgian Pro League |
| 12 | Sat 18 Oct | 53-1 v Sporting de CharleroiUnion Saint-Gilloise 3-1 Sporting de Charleroi | Belgian Pro League |
| 13 | Tue 21 Oct | 50-4 v Inter MilanUnion Saint-Gilloise 0-4 Inter Milan | UEFA Champions League Matchday 3 |
| 14 | Sun 26 Oct | 52-0 v Sint-Truidense VVUnion Saint-Gilloise 2-0 Sint-Truidense VV | Belgian Pro League |
| 15 | Sat 1 Nov | 54-1 v SV Zulte WaregemSV Zulte Waregem 1-4 Union Saint-Gilloise | Belgian Pro League |
| 16 | Tue 4 Nov | 5 1-3 v Atlético MadridAtlético Madrid 3-1 Union Saint-Gilloise | UEFA Champions League Matchday 4 |
| 17 | Sun 9 Nov | 51-1 v MechelenMechelen 1-1 Union Saint-Gilloise | Belgian Pro League |
| 18 | Sat 22 Nov | 52-0 v Cercle BruggeUnion Saint-Gilloise 2-0 Cercle Brugge | Belgian Pro League |
| 19 | Tue 25 Nov | 51-0 v GalatasarayGalatasaray 0-1 Union Saint-Gilloise | UEFA Champions League Matchday 5 |
| 20 | Sun 30 Nov | 50-1 v RSC AnderlechtRSC Anderlecht 1-0 Union Saint-Gilloise | Belgian Pro League |
| 21 | Sat 6 Dec | 5 1-1 v KAA GentUnion Saint-Gilloise 1-1 KAA Gent | Belgian Pro League |
| 22 | Tue 9 Dec | 52-3 v Olympique MarseilleUnion Saint-Gilloise 2-3 Olympique Marseille | UEFA Champions League Matchday 6 |
| 23 | Sun 14 Dec | 5 1-1 v Sporting de CharleroiSporting de Charleroi 1-1 Union Saint-Gilloise | Belgian Pro League |
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