| 1 | Sat 27 Jul | 490-0 v FCV Dender EHFCV Dender EH 0-0 Union Saint-Gilloise | Belgian First Division A |
| 2 | Fri 2 Aug | 493-1 v Germinal BeerschotUnion Saint-Gilloise 3-1 Germinal Beerschot | Belgian First Division A |
| 3 | Wed 7 Aug | 49 1-3 v Slavia PragueSlavia Prague 3-1 Union Saint-Gilloise | UEFA Champions League Third Qualifying Round |
| 4 | Sat 10 Aug | 493-4 v KVC WesterloKVC Westerlo 4-3 Union Saint-Gilloise | Belgian First Division A |
| 5 | Tue 13 Aug | 490-1 v Slavia PragueUnion Saint-Gilloise 0-1 Slavia Prague | UEFA Champions League Third Qualifying Round |
| 6 | Fri 16 Aug | 49 1-0 v Sporting de CharleroiUnion Saint-Gilloise 1-0 Sporting de Charleroi | Belgian First Division A |
| 7 | Sun 25 Aug | 490-0 v Sint-Truidense VVSint-Truidense VV 0-0 Union Saint-Gilloise | Belgian First Division A |
| 8 | Sun 1 Sep | 490-0 v RSC AnderlechtUnion Saint-Gilloise 0-0 RSC Anderlecht | Belgian First Division A |
| 9 | Sun 15 Sep | 490-2 v Royal AntwerpRoyal Antwerp 2-0 Union Saint-Gilloise | Belgian First Division A |
| 10 | Fri 20 Sep | 490-0 v Standard LiègeStandard Liège 0-0 Union Saint-Gilloise | Belgian First Division A |
| 11 | Thu 26 Sep | 491-2 v FenerbahçeFenerbahçe 2-1 Union Saint-Gilloise | UEFA Europa League Matchday 1 |
| 12 | Sun 29 Sep | 493-0 v KV KortrijkUnion Saint-Gilloise 3-0 KV Kortrijk | Belgian First Division A |
| 13 | Thu 3 Oct | 490-0 v FK Bodø/GlimtUnion Saint-Gilloise 0-0 FK Bodø/Glimt | UEFA Europa League Matchday 2 |
| 14 | Sun 6 Oct | 491-1 v Club BruggeClub Brugge 1-1 Union Saint-Gilloise | Belgian First Division A |
| 15 | Sat 19 Oct | 490-0 v KAA GentUnion Saint-Gilloise 0-0 KAA Gent | Belgian First Division A |
| 16 | Thu 24 Oct | 490-1 v FC MidtjyllandFC Midtjylland 1-0 Union Saint-Gilloise | UEFA Europa League Matchday 3 |
| 17 | Sun 27 Oct | 491-3 v Cercle BruggeUnion Saint-Gilloise 1-3 Cercle Brugge | Belgian First Division A |
| 18 | Sat 2 Nov | 49 1-1 v MechelenMechelen 1-1 Union Saint-Gilloise | Belgian First Division A |
| 19 | Thu 7 Nov | 491-1 v RomaUnion Saint-Gilloise 1-1 Roma | UEFA Europa League Matchday 4 |
| 20 | Sun 10 Nov | 494-0 v KRC GenkUnion Saint-Gilloise 4-0 KRC Genk | Belgian First Division A |
| 21 | Sun 24 Nov | 491-1 v Oud-Heverlee LeuvenOud-Heverlee Leuven 1-1 Union Saint-Gilloise | Belgian First Division A |
| 22 | Thu 28 Nov | 491-0 v FC TwenteFC Twente 0-1 Union Saint-Gilloise | UEFA Europa League Matchday 5 |
| 23 | Sun 1 Dec | 492-1 v Royal AntwerpUnion Saint-Gilloise 2-1 Royal Antwerp | Belgian First Division A |
| 24 | Sun 8 Dec | 490-0 v Cercle BruggeCercle Brugge 0-0 Union Saint-Gilloise | Belgian First Division A |
| 25 | Thu 12 Dec | 492-1 v NiceUnion Saint-Gilloise 2-1 Nice | UEFA Europa League Matchday 6 |
| 26 | Sun 15 Dec | 493-1 v KVC WesterloUnion Saint-Gilloise 3-1 KVC Westerlo | Belgian First Division A |
| 27 | Sun 22 Dec | 492-2 v Club BruggeUnion Saint-Gilloise 2-2 Club Brugge | Belgian First Division A |
| 28 | Thu 26 Dec | 493-1 v KAA GentKAA Gent 1-3 Union Saint-Gilloise | Belgian First Division A |
| 29 | Sat 11 Jan | 492-1 v Sporting de CharleroiSporting de Charleroi 1-2 Union Saint-Gilloise | Belgian First Division A |
| 30 | Sun 19 Jan | 491-0 v Oud-Heverlee LeuvenUnion Saint-Gilloise 1-0 Oud-Heverlee Leuven | Belgian First Division A |
| 31 | Thu 23 Jan | 492-1 v Sporting BragaUnion Saint-Gilloise 2-1 Sporting Braga | UEFA Europa League Matchday 7 |
| 32 | Sun 26 Jan | 494-0 v Germinal BeerschotGerminal Beerschot 0-4 Union Saint-Gilloise | Belgian First Division A |
| 33 | Thu 30 Jan | 491-2 v RangersRangers 2-1 Union Saint-Gilloise | UEFA Europa League Matchday 8 |
| 34 | Sun 2 Feb | 492-1 v Sint-Truidense VVUnion Saint-Gilloise 2-1 Sint-Truidense VV | Belgian First Division A |
| 35 | Sun 9 Feb | 492-1 v KV KortrijkKV Kortrijk 1-2 Union Saint-Gilloise | Belgian First Division A |
| 36 | Thu 13 Feb | 490-2 v AjaxUnion Saint-Gilloise 0-2 Ajax | UEFA Europa League Play-off Knockout Round |
| 37 | Sun 16 Feb | 490-1 v MechelenUnion Saint-Gilloise 0-1 Mechelen | Belgian First Division A |
| 38 | Thu 20 Feb | 492-1 v AjaxAjax 1-2 Union Saint-Gilloise | UEFA Europa League Play-off Knockout Round |
| 39 | Sun 23 Feb | 492-0 v RSC AnderlechtRSC Anderlecht 0-2 Union Saint-Gilloise | Belgian First Division A |
| 40 | Sat 1 Mar | 494-1 v FCV Dender EHUnion Saint-Gilloise 4-1 FCV Dender EH | Belgian First Division A |
| 41 | Sun 9 Mar | 493-0 v Standard LiègeUnion Saint-Gilloise 3-0 Standard Liège | Belgian First Division A |
| 42 | Sat 15 Mar | 491-2 v KRC GenkKRC Genk 2-1 Union Saint-Gilloise | Belgian First Division A |
| 43 | Sat 29 Mar | 495-1 v Royal AntwerpUnion Saint-Gilloise 5-1 Royal Antwerp | Belgian First Division A Play-off |
| 44 | Sat 5 Apr | 493-0 v KAA GentKAA Gent 0-3 Union Saint-Gilloise | Belgian First Division A Play-off |
| 45 | Sat 12 Apr | 492-0 v RSC AnderlechtUnion Saint-Gilloise 2-0 RSC Anderlecht | Belgian First Division A Play-off |
| 46 | Sun 20 Apr | 492-1 v KRC GenkKRC Genk 1-2 Union Saint-Gilloise | Belgian First Division A Play-off |
| 47 | Thu 24 Apr | 491-0 v Club BruggeClub Brugge 0-1 Union Saint-Gilloise | Belgian First Division A Play-off |
| 48 | Sun 27 Apr | 490-0 v Club BruggeUnion Saint-Gilloise 0-0 Club Brugge | Belgian First Division A Play-off |
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