| 1 | Sat 30 Aug | 331-3 v Eintracht FrankfurtTSG Hoffenheim 1-3 Eintracht Frankfurt | German Bundesliga |
| 2 | Sat 13 Sep | 334-2 v Union BerlinUnion Berlin 2-4 TSG Hoffenheim | German Bundesliga |
| 3 | Fri 3 Oct | 330-1 v 1 FC KölnTSG Hoffenheim 0-1 1 FC Köln | German Bundesliga |
| 4 | Sun 19 Oct | 333-0 v FC St PauliFC St Pauli 0-3 TSG Hoffenheim | German Bundesliga |
| 5 | Sat 25 Oct | 333-1 v 1 FC HeidenheimTSG Hoffenheim 3-1 1 FC Heidenheim | German Bundesliga |
| 6 | Sun 2 Nov | 333-2 v VfL WolfsburgVfL Wolfsburg 2-3 TSG Hoffenheim | German Bundesliga |
| 7 | Fri 21 Nov | 331-1 v Mainz 05Mainz 05 1-1 TSG Hoffenheim | German Bundesliga |
| 8 | Sat 29 Nov | 33 3-0 v FC AugsburgTSG Hoffenheim 3-0 FC Augsburg | German Bundesliga |
| 9 | Sun 7 Dec | 330-2 v Borussia DortmundBorussia Dortmund 2-0 TSG Hoffenheim | German Bundesliga |
| 10 | Wed 14 Jan | 335-1 v Borussia MönchengladbachTSG Hoffenheim 5-1 Borussia Mönchengladbach | German Bundesliga |
| 11 | Sat 17 Jan | 331-0 v Bayer LeverkusenTSG Hoffenheim 1-0 Bayer Leverkusen | German Bundesliga |
| 12 | Sat 24 Jan | 333-1 v Eintracht FrankfurtEintracht Frankfurt 1-3 TSG Hoffenheim | German Bundesliga |
| 13 | Tue 27 Jan | 332-0 v Werder BremenWerder Bremen 0-2 TSG Hoffenheim | German Bundesliga |
| 14 | Sat 31 Jan | 333-1 v Union BerlinTSG Hoffenheim 3-1 Union Berlin | German Bundesliga |
| 15 | Sun 8 Feb | 331-5 v Bayern MunichBayern Munich 5-1 TSG Hoffenheim | German Bundesliga |
| 16 | Sat 14 Feb | 333-0 v SC FreiburgTSG Hoffenheim 3-0 SC Freiburg | German Bundesliga |
| 17 | Sat 21 Feb | 33 2-2 v 1 FC Köln1 FC Köln 2-2 TSG Hoffenheim | German Bundesliga |
| 18 | Fri 20 Mar | 330-5 v RB LeipzigRB Leipzig 5-0 TSG Hoffenheim | German Bundesliga |
| 19 | Sat 4 Apr | 331-2 v Mainz 05TSG Hoffenheim 1-2 Mainz 05 | German Bundesliga |
| 20 | Sat 18 Apr | 332-1 v Borussia DortmundTSG Hoffenheim 2-1 Borussia Dortmund | German Bundesliga |
| 21 | Sat 25 Apr | 332-1 v Hamburger SVHamburger SV 1-2 TSG Hoffenheim | German Bundesliga |
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