| 1 | Mon 16 Aug 2021 | 15-1 v Yeni MalatyasporYeni Malatyaspor 1-5 Trabzonspor | Turkish Süper Lig |
| 2 | Mon 23 Aug 2021 | 1 2-1 v SivassporTrabzonspor 2-1 Sivasspor | Turkish Süper Lig |
| 3 | Thu 26 Aug 2021 | 10-3 v RomaRoma 3-0 Trabzonspor | UEFA Europa Conference League |
| 4 | Sun 29 Aug 2021 | 11-0 v GiresunsporGiresunspor 0-1 Trabzonspor | Turkish Süper Lig |
| 5 | Sun 12 Sep 2021 | 12-2 v GalatasarayTrabzonspor 2-2 Galatasaray | Turkish Süper Lig |
| 6 | Sat 18 Sep 2021 | 11-0 v Kasımpaşa SKKasımpaşa SK 0-1 Trabzonspor | Turkish Süper Lig |
| 7 | Thu 23 Sep 2021 | 12-2 v KonyasporKonyaspor 2-2 Trabzonspor | Turkish Süper Lig |
| 8 | Mon 27 Sep 2021 | 11-1 v AlanyasporTrabzonspor 1-1 Alanyaspor | Turkish Süper Lig |
| 9 | Sat 2 Oct 2021 | 12-1 v KayserisporKayserispor 1-2 Trabzonspor | Turkish Süper Lig |
| 10 | Sun 17 Oct 2021 | 13-1 v FenerbahçeTrabzonspor 3-1 Fenerbahçe | Turkish Süper Lig |
| 11 | Sat 23 Oct 2021 | 11-0 v Göztepe SKGöztepe SK 0-1 Trabzonspor | Turkish Süper Lig |
| 12 | Fri 29 Oct 2021 | 12-1 v Çaykur RizesporTrabzonspor 2-1 Çaykur Rizespor | Turkish Süper Lig |
| 13 | Sat 6 Nov 2021 | 1 2-1 v BeşiktaşBeşiktaş 1-2 Trabzonspor | Turkish Süper Lig |
| 14 | Sun 28 Nov 2021 | 12-0 v Fatih KaragümrükFatih Karagümrük 0-2 Trabzonspor | Turkish Süper Lig |
| 15 | Sat 4 Dec 2021 | 12-0 v Adana DemirsporTrabzonspor 2-0 Adana Demirspor | Turkish Süper Lig |
| 16 | Sat 11 Dec 2021 | 11-2 v AntalyasporAntalyaspor 2-1 Trabzonspor | Turkish Süper Lig |
| 17 | Sat 18 Dec 2021 | 12-0 v HataysporTrabzonspor 2-0 Hatayspor | Turkish Süper Lig |
| 18 | Tue 21 Dec 2021 | 12-1 v AltayAltay 1-2 Trabzonspor | Turkish Süper Lig |
| 19 | Sat 25 Dec 2021 | 10-0 v İstanbul BaşakşehirTrabzonspor 0-0 İstanbul Başakşehir | Turkish Süper Lig |
| 20 | Fri 7 Jan 2022 | 11-0 v Yeni MalatyasporTrabzonspor 1-0 Yeni Malatyaspor | Turkish Süper Lig |
| 21 | Sat 15 Jan 2022 | 11-1 v SivassporSivasspor 1-1 Trabzonspor | Turkish Süper Lig |
| 22 | Wed 19 Jan 2022 | 11-1 v GiresunsporTrabzonspor 1-1 Giresunspor | Turkish Süper Lig |
| 23 | Sun 23 Jan 2022 | 1 2-1 v GalatasarayGalatasaray 1-2 Trabzonspor | Turkish Süper Lig |
| 24 | Sat 5 Feb 2022 | 11-0 v Kasımpaşa SKTrabzonspor 1-0 Kasımpaşa SK | Turkish Süper Lig |
| 25 | Sun 13 Feb 2022 | 12-1 v KonyasporTrabzonspor 2-1 Konyaspor | Turkish Süper Lig |
| 26 | Sun 20 Feb 2022 | 14-0 v AlanyasporAlanyaspor 0-4 Trabzonspor | Turkish Süper Lig |
| 27 | Fri 25 Feb 2022 | 13-2 v KayserisporTrabzonspor 3-2 Kayserispor | Turkish Süper Lig |
| 28 | Sun 6 Mar 2022 | 11-1 v FenerbahçeFenerbahçe 1-1 Trabzonspor | Turkish Süper Lig |
| 29 | Sat 12 Mar 2022 | 1 4-2 v Göztepe SKTrabzonspor 4-2 Göztepe SK | Turkish Süper Lig |
| 30 | Sun 3 Apr 2022 | 11-1 v BeşiktaşTrabzonspor 1-1 Beşiktaş | Turkish Süper Lig |
| 31 | Sat 9 Apr 2022 | 10-0 v Gazişehir GaziantepGazişehir Gaziantep 0-0 Trabzonspor | Turkish Süper Lig |
| 32 | Fri 15 Apr 2022 | 11-1 v Fatih KaragümrükTrabzonspor 1-1 Fatih Karagümrük | Turkish Süper Lig |
| 33 | Sat 23 Apr 2022 | 1 3-1 v Adana DemirsporAdana Demirspor 1-3 Trabzonspor | Turkish Süper Lig |
| 34 | Sat 30 Apr 2022 | 12-2 v AntalyasporTrabzonspor 2-2 Antalyaspor | Turkish Süper Lig |
| 35 | Fri 6 May 2022 | 11-1 v HataysporHatayspor 1-1 Trabzonspor | Turkish Süper Lig |
| 36 | Sun 15 May 2022 | 12-1 v AltayTrabzonspor 2-1 Altay | Turkish Süper Lig |
| 37 | Sun 22 May 2022 | 11-3 v İstanbul Başakşehirİstanbul Başakşehir 3-1 Trabzonspor | Turkish Süper Lig |
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