| 1 | Sat 31 Jul 2021 | 162-2 v DundeeDundee 2-2 St Mirren | Cinch Premiership |
| 2 | Sat 21 Aug 2021 | 160-6 v CelticCeltic 6-0 St Mirren | Cinch Premiership |
| 3 | Sun 29 Aug 2021 | 16 0-0 v St JohnstoneSt Mirren 0-0 St Johnstone | Cinch Premiership |
| 4 | Sat 18 Sep 2021 | 162-2 v HibernianHibernian 2-2 St Mirren | Cinch Premiership |
| 5 | Sun 26 Sep 2021 | 163-2 v AberdeenSt Mirren 3-2 Aberdeen | Cinch Premiership |
| 6 | Sat 2 Oct 2021 | 161-0 v LivingstonLivingston 0-1 St Mirren | Cinch Premiership |
| 7 | Sat 16 Oct 2021 | 163-2 v Ross CountyRoss County 2-3 St Mirren | Cinch Premiership |
| 8 | Sun 24 Oct 2021 | 161-2 v RangersSt Mirren 1-2 Rangers | Cinch Premiership |
| 9 | Sat 4 Dec 2021 | 161-4 v AberdeenAberdeen 4-1 St Mirren | Cinch Premiership |
| 10 | Sun 26 Dec 2021 | 16 0-2 v RangersRangers 2-0 St Mirren | Cinch Premiership |
| 11 | Tue 18 Jan 2022 | 162-1 v Dundee UnitedDundee United 1-2 St Mirren | Cinch Premiership |
| 12 | Tue 25 Jan 2022 | 161-0 v AberdeenSt Mirren 1-0 Aberdeen | Cinch Premiership |
| 13 | Tue 1 Feb 2022 | 161-1 v MotherwellSt Mirren 1-1 Motherwell | Cinch Premiership |
| 14 | Sat 5 Feb 2022 | 161-0 v HibernianHibernian 0-1 St Mirren | Cinch Premiership |
| 15 | Wed 2 Mar 2022 | 160-2 v CelticCeltic 2-0 St Mirren | Cinch Premiership |
| 16 | Sat 5 Mar 2022 | 16 0-1 v Ross CountyRoss County 1-0 St Mirren | Cinch Premiership |
| 17 | Sat 19 Mar 2022 | 161-2 v Dundee UnitedSt Mirren 1-2 Dundee United | Cinch Premiership |
| 18 | Sat 2 Apr 2022 | 162-4 v MotherwellMotherwell 4-2 St Mirren | Cinch Premiership |
| 19 | Sun 10 Apr 2022 | 160-4 v RangersSt Mirren 0-4 Rangers | Cinch Premiership |
| 20 | Sat 23 Apr 2022 | 160-1 v HibernianSt Mirren 0-1 Hibernian | Cinch Premiership |
| 21 | Sat 7 May 2022 | 16 2-0 v DundeeSt Mirren 2-0 Dundee | Cinch Premiership |
| 22 | Wed 11 May 2022 | 160-0 v LivingstonSt Mirren 0-0 Livingston | Cinch Premiership |
| 23 | Sun 15 May 2022 | 16 0-0 v AberdeenAberdeen 0-0 St Mirren | Cinch Premiership |
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