| 1 | Thu 26 Aug 2021 | 241-2 v SochiSpartak Moscow 1-2 Sochi | Russian Premier League |
| 2 | Sat 11 Sep 2021 | 243-1 v KhimkiSpartak Moscow 3-1 Khimki | Russian Premier League |
| 3 | Wed 15 Sep 2021 | 240-1 v Legia WarsawSpartak Moscow 0-1 Legia Warsaw | UEFA Europa League Group C |
| 4 | Mon 20 Sep 2021 | 240-1 v CSKA MoscowCSKA Moscow 1-0 Spartak Moscow | Russian Premier League |
| 5 | Sat 25 Sep 2021 | 242-0 v UfaSpartak Moscow 2-0 Ufa | Russian Premier League |
| 6 | Thu 30 Sep 2021 | 243-2 v NapoliNapoli 2-3 Spartak Moscow | UEFA Europa League Group C |
| 7 | Sun 3 Oct 2021 | 241-0 v Akhmat GroznyAkhmat Grozny 0-1 Spartak Moscow | Russian Premier League |
| 8 | Sun 24 Oct 2021 | 241-7 v Zenit St PetersburgZenit St Petersburg 7-1 Spartak Moscow | Russian Premier League |
| 9 | Sat 30 Oct 2021 | 241-1 v RostovSpartak Moscow 1-1 Rostov | Russian Premier League |
| 10 | Thu 4 Nov 2021 | 241-1 v Leicester CityLeicester City 1-1 Spartak Moscow | UEFA Europa League Group C |
| 11 | Sun 7 Nov 2021 | 241-1 v Lokomotiv MoscowSpartak Moscow 1-1 Lokomotiv Moscow | Russian Premier League |
| 12 | Sat 20 Nov 2021 | 241-2 v FK KrasnodarFK Krasnodar 2-1 Spartak Moscow | Russian Premier League |
| 13 | Wed 24 Nov 2021 | 24 2-1 v NapoliSpartak Moscow 2-1 Napoli | UEFA Europa League Group C |
| 14 | Mon 29 Nov 2021 | 241-1 v UfaUfa 1-1 Spartak Moscow | Russian Premier League |
| 15 | Sat 4 Dec 2021 | 24 2-1 v Akhmat GroznySpartak Moscow 2-1 Akhmat Grozny | Russian Premier League |
| 16 | Thu 9 Dec 2021 | 24 1-0 v Legia WarsawLegia Warsaw 0-1 Spartak Moscow | UEFA Europa League Group C |
| 17 | Mon 13 Dec 2021 | 240-3 v SochiSochi 3-0 Spartak Moscow | Russian Premier League |
| 18 | Sat 26 Feb 2022 | 240-2 v CSKA MoscowSpartak Moscow 0-2 CSKA Moscow | Russian Premier League |
| 19 | Sun 6 Mar 2022 | 242-0 v Dinamo MoscowDinamo Moscow 0-2 Spartak Moscow | Russian Premier League |
| 20 | Sun 13 Mar 2022 | 241-2 v FK KrasnodarSpartak Moscow 1-2 FK Krasnodar | Russian Premier League |
| 21 | Sat 19 Mar 2022 | 241-1 v Nizhny NovgorodNizhny Novgorod 1-1 Spartak Moscow | Russian Premier League |
| 22 | Sat 2 Apr 2022 | 240-1 v Lokomotiv MoscowLokomotiv Moscow 1-0 Spartak Moscow | Russian Premier League |
| 23 | Sat 7 May 2022 | 243-1 v UralUral 1-3 Spartak Moscow | Russian Premier League |
| 24 | Sun 15 May 2022 | 241-1 v Zenit St PetersburgSpartak Moscow 1-1 Zenit St Petersburg | Russian Premier League |
| 25 | Sat 21 May 2022 | 241-2 v KhimkiKhimki 2-1 Spartak Moscow | Russian Premier League |
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