| 1 | Sun 15 Aug 2021 | 10-4 v FC UtrechtFC Utrecht 4-0 Sparta Rotterdam | Dutch Eredivisie |
| 2 | Sat 21 Aug 2021 | 11-1 v Heracles AlmeloSparta Rotterdam 1-1 Heracles Almelo | Dutch Eredivisie |
| 3 | Sat 28 Aug 2021 | 10-2 v Go Ahead EaglesGo Ahead Eagles 2-0 Sparta Rotterdam | Dutch Eredivisie |
| 4 | Sun 12 Sep 2021 | 13-1 v Fortuna SittardSparta Rotterdam 3-1 Fortuna Sittard | Dutch Eredivisie |
| 5 | Fri 17 Sep 2021 | 11-1 v NEC NijmegenSparta Rotterdam 1-1 NEC Nijmegen | Dutch Eredivisie |
| 6 | Wed 22 Sep 2021 | 11-1 v PEC ZwollePEC Zwolle 1-1 Sparta Rotterdam | Dutch Eredivisie |
| 7 | Sun 3 Oct 2021 | 1 1-2 v PSV EindhovenPSV Eindhoven 2-1 Sparta Rotterdam | Dutch Eredivisie |
| 8 | Sun 17 Oct 2021 | 1 1-1 v FC GroningenSparta Rotterdam 1-1 FC Groningen | Dutch Eredivisie |
| 9 | Sat 23 Oct 2021 | 10-1 v RKC WaalwijkRKC Waalwijk 1-0 Sparta Rotterdam | Dutch Eredivisie |
| 10 | Sun 31 Oct 2021 | 10-1 v FeyenoordSparta Rotterdam 0-1 Feyenoord | Dutch Eredivisie |
| 11 | Sat 6 Nov 2021 | 13-0 v Willem IIWillem II 0-3 Sparta Rotterdam | Dutch Eredivisie |
| 12 | Sat 20 Nov 2021 | 10-1 v FC TwenteSparta Rotterdam 0-1 FC Twente | Dutch Eredivisie |
| 13 | Sun 28 Nov 2021 | 10-1 v AjaxSparta Rotterdam 0-1 Ajax | Dutch Eredivisie |
| 14 | Sat 18 Dec 2021 | 12-2 v VitesseSparta Rotterdam 2-2 Vitesse | Dutch Eredivisie |
| 15 | Thu 23 Dec 2021 | 11-1 v RKC WaalwijkSparta Rotterdam 1-1 RKC Waalwijk | Dutch Eredivisie |
| 16 | Sun 6 Feb 2022 | 10-4 v FeyenoordFeyenoord 4-0 Sparta Rotterdam | Dutch Eredivisie |
| 17 | Sun 13 Feb 2022 | 11-0 v Willem IISparta Rotterdam 1-0 Willem II | Dutch Eredivisie |
| 18 | Sun 27 Feb 2022 | 11-2 v PSV EindhovenSparta Rotterdam 1-2 PSV Eindhoven | Dutch Eredivisie |
| 19 | Sat 12 Mar 2022 | 11-0 v Go Ahead EaglesSparta Rotterdam 1-0 Go Ahead Eagles | Dutch Eredivisie |
| 20 | Sat 19 Mar 2022 | 10-0 v NEC NijmegenNEC Nijmegen 0-0 Sparta Rotterdam | Dutch Eredivisie |
| 21 | Sun 3 Apr 2022 | 11-1 v sc HeerenveenSparta Rotterdam 1-1 sc Heerenveen | Dutch Eredivisie |
| 22 | Sat 9 Apr 2022 | 11-2 v AjaxAjax 2-1 Sparta Rotterdam | Dutch Eredivisie |
| 23 | Sat 16 Apr 2022 | 1 0-3 v Fortuna SittardFortuna Sittard 3-0 Sparta Rotterdam | Dutch Eredivisie |
| 24 | Tue 19 Apr 2022 | 11-0 v VitesseVitesse 0-1 Sparta Rotterdam | Dutch Eredivisie |
| 25 | Fri 22 Apr 2022 | 10-2 v FC TwenteFC Twente 2-0 Sparta Rotterdam | Dutch Eredivisie |
| 26 | Sat 30 Apr 2022 | 11-1 v AZ AlkmaarSparta Rotterdam 1-1 AZ Alkmaar | Dutch Eredivisie |
| 27 | Sat 7 May 2022 | 12-1 v FC GroningenFC Groningen 1-2 Sparta Rotterdam | Dutch Eredivisie |
| 28 | Wed 11 May 2022 | 12-0 v PEC ZwolleSparta Rotterdam 2-0 PEC Zwolle | Dutch Eredivisie |
| 29 | Sun 15 May 2022 | 13-1 v Heracles AlmeloHeracles Almelo 1-3 Sparta Rotterdam | Dutch Eredivisie |
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