| 1 | Fri 22 Aug | 161-0 v AlavésReal Betis 1-0 Alavés |
| 2 | Wed 27 Aug | 161-1 v Celta VigoCelta Vigo 1-1 Real Betis |
| 3 | Sun 14 Sep | 162-2 v LevanteLevante 2-2 Real Betis |
| 4 | Fri 19 Sep | 163-1 v Real SociedadReal Betis 3-1 Real Sociedad |
| 5 | Sun 28 Sep | 162-0 v OsasunaReal Betis 2-0 Osasuna |
| 6 | Sun 5 Oct | 16 2-1 v EspanyolEspanyol 1-2 Real Betis |
| 7 | Sat 18 Oct | 162-2 v VillarrealVillarreal 2-2 Real Betis |
| 8 | Sun 2 Nov | 163-0 v MallorcaReal Betis 3-0 Mallorca |
| 9 | Sun 9 Nov | 16 1-1 v ValenciaValencia 1-1 Real Betis |
| 10 | Sun 23 Nov | 161-1 v GironaReal Betis 1-1 Girona |
| 11 | Sun 30 Nov | 162-0 v SevillaSevilla 0-2 Real Betis |
| 12 | Sat 6 Dec | 16 3-5 v BarcelonaReal Betis 3-5 Barcelona |
| 13 | Sun 21 Dec | 164-0 v GetafeReal Betis 4-0 Getafe |
| 14 | Sat 10 Jan | 161-1 v Real OviedoReal Oviedo 1-1 Real Betis |
| 15 | Sat 17 Jan | 16 2-0 v VillarrealReal Betis 2-0 Villarreal |
| 16 | Sun 25 Jan | 161-2 v AlavésAlavés 2-1 Real Betis |
| 17 | Sun 1 Feb | 162-1 v ValenciaReal Betis 2-1 Valencia |
| 18 | Sat 21 Feb | 16 1-1 v Rayo VallecanoReal Betis 1-1 Rayo Vallecano |
| 19 | Sun 8 Mar | 160-2 v GetafeGetafe 2-0 Real Betis |
| 20 | Sun 15 Mar | 161-1 v Celta VigoReal Betis 1-1 Celta Vigo |
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