| 1 | Sat 8 Aug 2015 | 11-1 v Fleetwood TownFleetwood Town 1-1 Southend United | Sky Bet League One |
| 2 | Tue 11 Aug 2015 | 10-1 v Brighton & Hove AlbionSouthend United 0-1 Brighton & Hove Albion | Capital One Cup First Round |
| 3 | Sat 15 Aug 2015 | 10-2 v WalsallSouthend United 0-2 Walsall | Sky Bet League One |
| 4 | Wed 19 Aug 2015 | 10-0 v Doncaster RoversDoncaster Rovers 0-0 Southend United | Sky Bet League One |
| 5 | Sat 22 Aug 2015 | 10-1 v Swindon TownSouthend United 0-1 Swindon Town | Sky Bet League One |
| 6 | Mon 31 Aug 2015 | 12-2 v Coventry CityCoventry City 2-2 Southend United | Sky Bet League One |
| 7 | Sat 5 Sep 2015 | 12-1 v Peterborough UnitedSouthend United 2-1 Peterborough United | Sky Bet League One |
| 8 | Sat 12 Sep 2015 | 10-1 v Shrewsbury TownSouthend United 0-1 Shrewsbury Town | Sky Bet League One |
| 9 | Sat 19 Sep 2015 | 12-0 v MillwallMillwall 0-2 Southend United | Sky Bet League One |
| 10 | Sat 26 Sep 2015 | 12-1 v Scunthorpe UnitedSouthend United 2-1 Scunthorpe United | Sky Bet League One |
| 11 | Tue 29 Sep 2015 | 12-1 v Crewe AlexandraCrewe Alexandra 1-2 Southend United | Sky Bet League One |
| 12 | Sat 3 Oct 2015 | 10-1 v Burton AlbionBurton Albion 1-0 Southend United | Sky Bet League One |
| 13 | Tue 6 Oct 2015 | 13-0 v Crawley TownCrawley Town 0-3 Southend United | Johnstone's Paint Trophy Southern Area Second Round |
| 14 | Sat 10 Oct 2015 | 11-0 v Port ValeSouthend United 1-0 Port Vale | Sky Bet League One |
| 15 | Sat 17 Oct 2015 | 12-1 v BarnsleySouthend United 2-1 Barnsley | Sky Bet League One |
| 16 | Tue 20 Oct 2015 | 10-3 v ChesterfieldChesterfield 3-0 Southend United | Sky Bet League One |
| 17 | Sat 24 Oct 2015 | 11-1 v GillinghamGillingham 1-1 Southend United | Sky Bet League One |
| 18 | Sat 31 Oct 2015 | 12-2 v RochdaleSouthend United 2-2 Rochdale | Sky Bet League One |
| 19 | Sat 7 Nov 2015 | 11-2 v Scunthorpe UnitedScunthorpe United 2-1 Southend United | Emirates FA Cup First Round |
| 20 | Wed 11 Nov 2015 | 11-0 v Bristol RoversSouthend United 1-0 Bristol Rovers | Johnstone's Paint Trophy Southern Area Quarter Final |
| 21 | Sat 14 Nov 2015 | 12-2 v Sheffield UnitedSheffield United 2-2 Southend United | Sky Bet League One |
| 22 | Sat 21 Nov 2015 | 11-0 v BlackpoolSouthend United 1-0 Blackpool | Sky Bet League One |
| 23 | Tue 24 Nov 2015 | 15-2 v Oldham AthleticOldham Athletic 2-5 Southend United | Sky Bet League One |
| 24 | Sat 28 Nov 2015 | 10-0 v Wigan AthleticSouthend United 0-0 Wigan Athletic | Sky Bet League One |
| 25 | Tue 8 Dec 2015 | 10-2 v MillwallSouthend United 0-2 Millwall | Johnstone's Paint Trophy Southern Area Semi Final |
| 26 | Fri 18 Dec 2015 | 14-1 v BurySouthend United 4-1 Bury | Sky Bet League One |
| 27 | Sat 26 Dec 2015 | 12-0 v Colchester UnitedColchester United 0-2 Southend United | Sky Bet League One |
| 28 | Mon 28 Dec 2015 | 10-4 v MillwallSouthend United 0-4 Millwall | Sky Bet League One |
| 29 | Sat 2 Jan 2016 | 10-3 v Doncaster RoversSouthend United 0-3 Doncaster Rovers | Sky Bet League One |
| 30 | Sat 9 Jan 2016 | 12-4 v Swindon TownSwindon Town 4-2 Southend United | Sky Bet League One |
| 31 | Sat 16 Jan 2016 | 10-0 v Peterborough UnitedPeterborough United 0-0 Southend United | Sky Bet League One |
| 32 | Sat 23 Jan 2016 | 13-0 v Coventry CitySouthend United 3-0 Coventry City | Sky Bet League One |
| 33 | Tue 2 Feb 2016 | 12-1 v Shrewsbury TownShrewsbury Town 1-2 Southend United | Sky Bet League One |
| 34 | Sat 6 Feb 2016 | 13-0 v Colchester UnitedSouthend United 3-0 Colchester United | Sky Bet League One |
| 35 | Sat 13 Feb 2016 | 10-1 v Scunthorpe UnitedScunthorpe United 1-0 Southend United | Sky Bet League One |
| 36 | Tue 16 Feb 2016 | 10-2 v Bradford CityBradford City 2-0 Southend United | Sky Bet League One |
| 37 | Mon 22 Feb 2016 | 13-1 v Burton AlbionSouthend United 3-1 Burton Albion | Sky Bet League One |
| 38 | Fri 26 Feb 2016 | 11-3 v Port ValePort Vale 3-1 Southend United | Sky Bet League One |
| 39 | Tue 1 Mar 2016 | 11-1 v Crewe AlexandraSouthend United 1-1 Crewe Alexandra | Sky Bet League One |
| 40 | Sat 5 Mar 2016 | 10-1 v ChesterfieldSouthend United 0-1 Chesterfield | Sky Bet League One |
| 41 | Sat 12 Mar 2016 | 12-0 v BarnsleyBarnsley 0-2 Southend United | Sky Bet League One |
| 42 | Sat 19 Mar 2016 | 11-1 v GillinghamSouthend United 1-1 Gillingham | Sky Bet League One |
| 43 | Fri 25 Mar 2016 | 11-4 v RochdaleRochdale 4-1 Southend United | Sky Bet League One |
| 44 | Wed 30 Mar 2016 | 13-1 v Sheffield UnitedSouthend United 3-1 Sheffield United | Sky Bet League One |
| 45 | Sat 2 Apr 2016 | 10-2 v BlackpoolBlackpool 2-0 Southend United | Sky Bet League One |
| 46 | Sat 9 Apr 2016 | 12-2 v Fleetwood TownSouthend United 2-2 Fleetwood Town | Sky Bet League One |
| 47 | Sat 16 Apr 2016 | 10-1 v WalsallWalsall 1-0 Southend United | Sky Bet League One |
| 48 | Tue 19 Apr 2016 | 10-1 v Oldham AthleticSouthend United 0-1 Oldham Athletic | Sky Bet League One |
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