| 1 | Sat 8 Aug 2015 | 41-1 v Fleetwood TownFleetwood Town 1-1 Southend United | Sky Bet League One |
| 2 | Tue 11 Aug 2015 | 40-1 v Brighton & Hove AlbionSouthend United 0-1 Brighton & Hove Albion | Capital One Cup First Round |
| 3 | Sat 15 Aug 2015 | 40-2 v WalsallSouthend United 0-2 Walsall | Sky Bet League One |
| 4 | Sat 22 Aug 2015 | 40-1 v Swindon TownSouthend United 0-1 Swindon Town | Sky Bet League One |
| 5 | Mon 31 Aug 2015 | 42-2 v Coventry CityCoventry City 2-2 Southend United | Sky Bet League One |
| 6 | Sat 5 Sep 2015 | 42-1 v Peterborough UnitedSouthend United 2-1 Peterborough United | Sky Bet League One |
| 7 | Sat 12 Sep 2015 | 40-1 v Shrewsbury TownSouthend United 0-1 Shrewsbury Town | Sky Bet League One |
| 8 | Sat 3 Oct 2015 | 40-1 v Burton AlbionBurton Albion 1-0 Southend United | Sky Bet League One |
| 9 | Tue 6 Oct 2015 | 43-0 v Crawley TownCrawley Town 0-3 Southend United | Johnstone's Paint Trophy Southern Area Second Round |
| 10 | Sat 10 Oct 2015 | 41-0 v Port ValeSouthend United 1-0 Port Vale | Sky Bet League One |
| 11 | Sat 17 Oct 2015 | 42-1 v BarnsleySouthend United 2-1 Barnsley | Sky Bet League One |
| 12 | Tue 20 Oct 2015 | 40-3 v ChesterfieldChesterfield 3-0 Southend United | Sky Bet League One |
| 13 | Sat 24 Oct 2015 | 41-1 v GillinghamGillingham 1-1 Southend United | Sky Bet League One |
| 14 | Sat 6 Feb 2016 | 43-0 v Colchester UnitedSouthend United 3-0 Colchester United | Sky Bet League One |
| 15 | Sat 13 Feb 2016 | 40-1 v Scunthorpe UnitedScunthorpe United 1-0 Southend United | Sky Bet League One |
| 16 | Tue 16 Feb 2016 | 40-2 v Bradford CityBradford City 2-0 Southend United | Sky Bet League One |
| 17 | Mon 22 Feb 2016 | 43-1 v Burton AlbionSouthend United 3-1 Burton Albion | Sky Bet League One |
| 18 | Fri 26 Feb 2016 | 41-3 v Port ValePort Vale 3-1 Southend United | Sky Bet League One |
| 19 | Tue 1 Mar 2016 | 41-1 v Crewe AlexandraSouthend United 1-1 Crewe Alexandra | Sky Bet League One |
| 20 | Sat 5 Mar 2016 | 40-1 v ChesterfieldSouthend United 0-1 Chesterfield | Sky Bet League One |
| 21 | Sat 12 Mar 2016 | 42-0 v BarnsleyBarnsley 0-2 Southend United | Sky Bet League One |
| 22 | Sat 19 Mar 2016 | 41-1 v GillinghamSouthend United 1-1 Gillingham | Sky Bet League One |
| 23 | Fri 25 Mar 2016 | 41-4 v RochdaleRochdale 4-1 Southend United | Sky Bet League One |
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