| 1 | Sat 17 Aug | 80-1 v Newcastle UnitedNewcastle United 1-0 Southampton | Premier League |
| 2 | Sat 24 Aug | 80-1 v Nottingham ForestSouthampton 0-1 Nottingham Forest | Premier League |
| 3 | Sat 31 Aug | 81-3 v BrentfordBrentford 3-1 Southampton | Premier League |
| 4 | Sat 19 Oct | 82-3 v Leicester CitySouthampton 2-3 Leicester City | Premier League |
| 5 | Sun 12 Jan | 83-0 v Swansea CitySouthampton 3-0 Swansea City | Emirates FA Cup Third Round |
| 6 | Thu 16 Jan | 81-3 v Manchester UnitedManchester United 3-1 Southampton | Premier League |
| 7 | Sun 19 Jan | 82-3 v Nottingham ForestNottingham Forest 3-2 Southampton | Premier League |
| 8 | Sat 25 Jan | 81-3 v Newcastle UnitedSouthampton 1-3 Newcastle United | Premier League |
| 9 | Sat 1 Feb | 82-1 v Ipswich TownIpswich Town 1-2 Southampton | Premier League |
| 10 | Sat 8 Feb | 80-1 v BurnleySouthampton 0-1 Burnley | Emirates FA Cup Fourth Round |
| 11 | Sat 15 Feb | 8 1-3 v AFC BournemouthSouthampton 1-3 AFC Bournemouth | Premier League |
| 12 | Sat 22 Feb | 80-4 v Brighton & Hove AlbionSouthampton 0-4 Brighton & Hove Albion | Premier League |
| 13 | Tue 25 Feb | 80-4 v ChelseaChelsea 4-0 Southampton | Premier League |
| 14 | Sat 8 Mar | 81-3 v LiverpoolLiverpool 3-1 Southampton | Premier League |
| 15 | Sun 6 Apr | 81-3 v Tottenham HotspurTottenham Hotspur 3-1 Southampton | Premier League |
| 16 | Sat 12 Apr | 80-3 v Aston VillaSouthampton 0-3 Aston Villa | Premier League |
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