| 1 | Sat 9 Aug | 112-1 v WrexhamSouthampton 2-1 Wrexham | Sky Bet Championship |
| 2 | Tue 12 Aug | 111-0 v Northampton TownNorthampton Town 0-1 Southampton | Carabao Cup First Round |
| 3 | Sat 23 Aug | 111-2 v Stoke CitySouthampton 1-2 Stoke City | Sky Bet Championship |
| 4 | Tue 26 Aug | 113-0 v Norwich CityNorwich City 0-3 Southampton | Carabao Cup Second Round |
| 5 | Sat 30 Aug | 112-2 v WatfordWatford 2-2 Southampton | Sky Bet Championship |
| 6 | Sun 14 Sep | 110-0 v PortsmouthSouthampton 0-0 Portsmouth | Sky Bet Championship |
| 7 | Sat 20 Sep | 11 1-3 v Hull CityHull City 3-1 Southampton | Sky Bet Championship |
| 8 | Tue 23 Sep | 111-2 v LiverpoolLiverpool 2-1 Southampton | Carabao Cup Third Round |
| 9 | Sat 27 Sep | 111-1 v MiddlesbroughSouthampton 1-1 Middlesbrough | Sky Bet Championship |
| 10 | Tue 30 Sep | 112-1 v Sheffield UnitedSheffield United 1-2 Southampton | Sky Bet Championship |
| 11 | Sat 4 Oct | 11 1-1 v Derby CountyDerby County 1-1 Southampton | Sky Bet Championship |
| 12 | Sun 4 Jan | 110-4 v MiddlesbroughMiddlesbrough 4-0 Southampton | Sky Bet Championship |
| 13 | Sat 10 Jan | 113-2 v Doncaster RoversDoncaster Rovers 2-3 Southampton | Emirates FA Cup Third Round |
| 14 | Sat 17 Jan | 111-2 v Hull CitySouthampton 1-2 Hull City | Sky Bet Championship |
| 15 | Wed 21 Jan | 111-0 v Sheffield UnitedSouthampton 1-0 Sheffield United | Sky Bet Championship |
| 16 | Sun 25 Jan | 111-1 v PortsmouthPortsmouth 1-1 Southampton | Sky Bet Championship |
| 17 | Sat 31 Jan | 112-0 v Stoke CityStoke City 0-2 Southampton | Sky Bet Championship |
| 18 | Sat 7 Feb | 111-0 v WatfordSouthampton 1-0 Watford | Sky Bet Championship |
| 19 | Tue 10 Feb | 114-3 v Leicester CityLeicester City 3-4 Southampton | Sky Bet Championship |
| 20 | Sat 21 Feb | 111-1 v Charlton AthleticSouthampton 1-1 Charlton Athletic | Sky Bet Championship |
| 21 | Tue 24 Feb | 115-0 v Queens Park RangersSouthampton 5-0 Queens Park Rangers | Sky Bet Championship |
| 22 | Sun 8 Mar | 111-0 v FulhamFulham 0-1 Southampton | Emirates FA Cup Fifth Round |
| 23 | Wed 11 Mar | 111-1 v West Bromwich AlbionWest Bromwich Albion 1-1 Southampton | Sky Bet Championship |
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