| 1 | Sat 21 Feb | 411-1 v Charlton AthleticSouthampton 1-1 Charlton Athletic | Sky Bet Championship |
| 2 | Tue 24 Feb | 415-0 v Queens Park RangersSouthampton 5-0 Queens Park Rangers | Sky Bet Championship |
| 3 | Sat 28 Feb | 413-1 v Sheffield WednesdaySheffield Wednesday 1-3 Southampton | Sky Bet Championship |
| 4 | Sun 8 Mar | 411-0 v FulhamFulham 0-1 Southampton | Emirates FA Cup Fifth Round |
| 5 | Wed 11 Mar | 411-1 v West Bromwich AlbionWest Bromwich Albion 1-1 Southampton | Sky Bet Championship |
| 6 | Sat 14 Mar | 41 2-1 v Coventry CityCoventry City 1-2 Southampton | Sky Bet Championship |
| 7 | Wed 18 Mar | 411-0 v Norwich CitySouthampton 1-0 Norwich City | Sky Bet Championship |
| 8 | Sat 21 Mar | 412-0 v Oxford UnitedSouthampton 2-0 Oxford United | Sky Bet Championship |
| 9 | Sat 4 Apr | 412-1 v ArsenalSouthampton 2-1 Arsenal | Emirates FA Cup Quarter Final |
| 10 | Tue 7 Apr | 415-1 v WrexhamWrexham 1-5 Southampton | Sky Bet Championship |
| 11 | Sat 11 Apr | 412-1 v Derby CountySouthampton 2-1 Derby County | Sky Bet Championship |
| 12 | Tue 14 Apr | 413-0 v Blackburn RoversSouthampton 3-0 Blackburn Rovers | Sky Bet Championship |
| 13 | Sat 18 Apr | 412-1 v Swansea CitySwansea City 1-2 Southampton | Sky Bet Championship |
| 14 | Tue 21 Apr | 412-2 v Bristol CitySouthampton 2-2 Bristol City | Sky Bet Championship |
| 15 | Sat 25 Apr | 411-2 v Manchester CityManchester City 2-1 Southampton | Emirates FA Cup Semi Final |
| 16 | Tue 28 Apr | 412-2 v Ipswich TownSouthampton 2-2 Ipswich Town | Sky Bet Championship |
| 17 | Sat 2 May | 413-1 v Preston North EndPreston North End 1-3 Southampton | Sky Bet Championship |
| 18 | Sat 9 May | 410-0 v MiddlesbroughMiddlesbrough 0-0 Southampton | Sky Bet Championship Play-off Semi Final |
| 19 | Tue 12 May | 41 2-1 v MiddlesbroughSouthampton 2-1 Middlesbrough | Sky Bet Championship Play-off Semi Final |
| 20 | Sat 8 Aug | 12-0 v Colchester UnitedColchester United 0-2 Southampton | Carabao Cup First Round |
| 21 | Sun 16 Aug | 11-2 v WatfordWatford 2-1 Southampton | Sky Bet Championship |
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