| 1 | Sat 9 Aug | 422-1 v WrexhamSouthampton 2-1 Wrexham | Sky Bet Championship |
| 2 | Tue 12 Aug | 421-0 v Northampton TownNorthampton Town 0-1 Southampton | Carabao Cup First Round |
| 3 | Sat 23 Aug | 421-2 v Stoke CitySouthampton 1-2 Stoke City | Sky Bet Championship |
| 4 | Tue 26 Aug | 423-0 v Norwich CityNorwich City 0-3 Southampton | Carabao Cup Second Round |
| 5 | Sat 30 Aug | 42 2-2 v WatfordWatford 2-2 Southampton | Sky Bet Championship |
| 6 | Sat 20 Sep | 421-3 v Hull CityHull City 3-1 Southampton | Sky Bet Championship |
| 7 | Tue 23 Sep | 421-2 v LiverpoolLiverpool 2-1 Southampton | Carabao Cup Third Round |
| 8 | Sat 4 Oct | 421-1 v Derby CountyDerby County 1-1 Southampton | Sky Bet Championship |
| 9 | Sat 1 Nov | 420-2 v Preston North EndSouthampton 0-2 Preston North End | Sky Bet Championship |
| 10 | Wed 5 Nov | 422-1 v Queens Park RangersQueens Park Rangers 1-2 Southampton | Sky Bet Championship |
| 11 | Sat 8 Nov | 423-1 v Sheffield WednesdaySouthampton 3-1 Sheffield Wednesday | Sky Bet Championship |
| 12 | Sat 22 Nov | 425-1 v Charlton AthleticCharlton Athletic 1-5 Southampton | Sky Bet Championship |
| 13 | Tue 25 Nov | 423-0 v Leicester CitySouthampton 3-0 Leicester City | Sky Bet Championship |
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