| 1 | Sat 6 Aug 2022 | 191-4 v Tottenham HotspurTottenham Hotspur 4-1 Southampton | Premier League |
| 2 | Sat 13 Aug 2022 | 192-2 v Leeds UnitedSouthampton 2-2 Leeds United | Premier League |
| 3 | Sat 20 Aug 2022 | 192-1 v Leicester CityLeicester City 1-2 Southampton | Premier League |
| 4 | Tue 23 Aug 2022 | 19 3-0 v Cambridge UnitedCambridge United 0-3 Southampton | Carabao Cup Second Round |
| 5 | Sat 27 Aug 2022 | 190-1 v Manchester UnitedSouthampton 0-1 Manchester United | Premier League |
| 6 | Tue 30 Aug 2022 | 192-1 v ChelseaSouthampton 2-1 Chelsea | Premier League |
| 7 | Sat 3 Sep 2022 | 190-1 v Wolverhampton WanderersWolverhampton Wanderers 1-0 Southampton | Premier League |
| 8 | Fri 16 Sep 2022 | 190-1 v Aston VillaAston Villa 1-0 Southampton | Premier League |
| 9 | Sat 8 Oct 2022 | 190-4 v Manchester CityManchester City 4-0 Southampton | Premier League |
| 10 | Wed 19 Oct 2022 | 191-0 v AFC BournemouthAFC Bournemouth 0-1 Southampton | Premier League |
| 11 | Sat 29 Oct 2022 | 190-1 v Crystal PalaceCrystal Palace 1-0 Southampton | Premier League |
| 12 | Wed 9 Nov 2022 | 191-1 v Sheffield WednesdaySouthampton 1-1 Sheffield Wednesday | Carabao Cup Third Round |
| 13 | Tue 20 Dec 2022 | 192-1 v Lincoln CitySouthampton 2-1 Lincoln City | Carabao Cup Fourth Round |
| 14 | Mon 26 Dec 2022 | 191-3 v Brighton & Hove AlbionSouthampton 1-3 Brighton & Hove Albion | Premier League |
| 15 | Sat 7 Jan 2023 | 192-1 v Crystal PalaceCrystal Palace 1-2 Southampton | Emirates FA Cup Third Round |
| 16 | Wed 11 Jan 2023 | 192-0 v Manchester CitySouthampton 2-0 Manchester City | Carabao Cup Quarter Final |
| 17 | Sat 21 Jan 2023 | 190-1 v Aston VillaSouthampton 0-1 Aston Villa | Premier League |
| 18 | Tue 24 Jan 2023 | 190-1 v Newcastle UnitedSouthampton 0-1 Newcastle United | Carabao Cup Semi Final |
| 19 | Wed 1 Mar 2023 | 191-2 v Grimsby TownSouthampton 1-2 Grimsby Town | Emirates FA Cup Fifth Round |
| 20 | Sat 8 Apr 2023 | 191-4 v Manchester CitySouthampton 1-4 Manchester City | Premier League |
| 21 | Sat 15 Apr 2023 | 190-2 v Crystal PalaceSouthampton 0-2 Crystal Palace | Premier League |
| 22 | Sun 30 Apr 2023 | 191-3 v Newcastle UnitedNewcastle United 3-1 Southampton | Premier League |
| 23 | Sat 13 May 2023 | 19 0-2 v FulhamSouthampton 0-2 Fulham | Premier League |
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