| 1 | Sat 28 Aug 2021 | 230-1 v MorecambeMorecambe 1-0 Sheffield Wednesday | Sky Bet League One |
| 2 | Sat 11 Sep 2021 | 230-3 v Plymouth ArgylePlymouth Argyle 3-0 Sheffield Wednesday | Sky Bet League One |
| 3 | Sat 18 Sep 2021 | 231-1 v Shrewsbury TownSheffield Wednesday 1-1 Shrewsbury Town | Sky Bet League One |
| 4 | Tue 5 Oct 2021 | 232-1 v Mansfield TownMansfield Town 1-2 Sheffield Wednesday | Papa John’s Trophy |
| 5 | Sat 23 Oct 2021 | 231-1 v Lincoln CitySheffield Wednesday 1-1 Lincoln City | Sky Bet League One |
| 6 | Sat 30 Oct 2021 | 232-2 v Cheltenham TownCheltenham Town 2-2 Sheffield Wednesday | Sky Bet League One |
| 7 | Tue 2 Nov 2021 | 233-0 v SunderlandSheffield Wednesday 3-0 Sunderland | Sky Bet League One |
| 8 | Sun 7 Nov 2021 | 230-0 v Plymouth ArgyleSheffield Wednesday 0-0 Plymouth Argyle | Emirates FA Cup First Round |
| 9 | Sat 13 Nov 2021 | 231-1 v GillinghamSheffield Wednesday 1-1 Gillingham | Sky Bet League One |
| 10 | Tue 16 Nov 2021 | 230-3 v Plymouth ArgylePlymouth Argyle 3-0 Sheffield Wednesday | Emirates FA Cup First Round Replay |
| 11 | Sat 20 Nov 2021 | 233-2 v Accrington StanleyAccrington Stanley 2-3 Sheffield Wednesday | Sky Bet League One |
| 12 | Tue 23 Nov 2021 | 232-1 v Milton Keynes DonsSheffield Wednesday 2-1 Milton Keynes Dons | Sky Bet League One |
| 13 | Sat 27 Nov 2021 | 232-2 v Wycombe WanderersSheffield Wednesday 2-2 Wycombe Wanderers | Sky Bet League One |
| 14 | Sat 11 Dec 2021 | 23 2-0 v Crewe AlexandraCrewe Alexandra 0-2 Sheffield Wednesday | Sky Bet League One |
| 15 | Thu 30 Dec 2021 | 230-5 v SunderlandSunderland 5-0 Sheffield Wednesday | Sky Bet League One |
| 16 | Sun 2 Jan 2022 | 230-1 v Shrewsbury TownShrewsbury Town 1-0 Sheffield Wednesday | Sky Bet League One |
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