| 1 | Sat 7 Aug 2021 | 200-0 v Charlton AthleticCharlton Athletic 0-0 Sheffield Wednesday | Sky Bet League One |
| 2 | Sat 14 Aug 2021 | 202-0 v Doncaster RoversSheffield Wednesday 2-0 Doncaster Rovers | Sky Bet League One |
| 3 | Tue 17 Aug 2021 | 201-0 v Fleetwood TownSheffield Wednesday 1-0 Fleetwood Town | Sky Bet League One |
| 4 | Sat 21 Aug 2021 | 202-0 v Rotherham UnitedRotherham United 0-2 Sheffield Wednesday | Sky Bet League One |
| 5 | Sat 28 Aug 2021 | 200-1 v MorecambeMorecambe 1-0 Sheffield Wednesday | Sky Bet League One |
| 6 | Sat 18 Sep 2021 | 201-1 v Shrewsbury TownSheffield Wednesday 1-1 Shrewsbury Town | Sky Bet League One |
| 7 | Tue 5 Oct 2021 | 202-1 v Mansfield TownMansfield Town 1-2 Sheffield Wednesday | Papa John’s Trophy |
| 8 | Sat 30 Oct 2021 | 202-2 v Cheltenham TownCheltenham Town 2-2 Sheffield Wednesday | Sky Bet League One |
| 9 | Tue 2 Nov 2021 | 203-0 v SunderlandSheffield Wednesday 3-0 Sunderland | Sky Bet League One |
| 10 | Sun 7 Nov 2021 | 200-0 v Plymouth ArgyleSheffield Wednesday 0-0 Plymouth Argyle | Emirates FA Cup First Round |
| 11 | Sat 13 Nov 2021 | 201-1 v GillinghamSheffield Wednesday 1-1 Gillingham | Sky Bet League One |
| 12 | Tue 16 Nov 2021 | 200-3 v Plymouth ArgylePlymouth Argyle 3-0 Sheffield Wednesday | Emirates FA Cup First Round Replay |
| 13 | Sat 20 Nov 2021 | 203-2 v Accrington StanleyAccrington Stanley 2-3 Sheffield Wednesday | Sky Bet League One |
| 14 | Tue 23 Nov 2021 | 202-1 v Milton Keynes DonsSheffield Wednesday 2-1 Milton Keynes Dons | Sky Bet League One |
| 15 | Sat 27 Nov 2021 | 202-2 v Wycombe WanderersSheffield Wednesday 2-2 Wycombe Wanderers | Sky Bet League One |
| 16 | Tue 7 Dec 2021 | 200-0 v PortsmouthPortsmouth 0-0 Sheffield Wednesday | Sky Bet League One |
| 17 | Sat 29 Jan 2022 | 201-0 v Ipswich TownSheffield Wednesday 1-0 Ipswich Town | Sky Bet League One |
| 18 | Tue 1 Feb 2022 | 202-0 v MorecambeSheffield Wednesday 2-0 Morecambe | Sky Bet League One |
| 19 | Sat 5 Feb 2022 | 202-0 v Burton AlbionBurton Albion 0-2 Sheffield Wednesday | Sky Bet League One |
| 20 | Tue 8 Feb 2022 | 201-0 v Wigan AthleticSheffield Wednesday 1-0 Wigan Athletic | Sky Bet League One |
| 21 | Sun 13 Feb 2022 | 200-2 v Rotherham UnitedSheffield Wednesday 0-2 Rotherham United | Sky Bet League One |
| 22 | Sat 19 Feb 2022 | 203-1 v Doncaster RoversDoncaster Rovers 1-3 Sheffield Wednesday | Sky Bet League One |
| 23 | Sat 26 Feb 2022 | 202-0 v Charlton AthleticSheffield Wednesday 2-0 Charlton Athletic | Sky Bet League One |
| 24 | Sat 5 Mar 2022 | 201-3 v Lincoln CityLincoln City 3-1 Sheffield Wednesday | Sky Bet League One |
| 25 | Sat 12 Mar 2022 | 206-0 v Cambridge UnitedSheffield Wednesday 6-0 Cambridge United | Sky Bet League One |
| 26 | Tue 19 Apr 2022 | 201-0 v Crewe AlexandraSheffield Wednesday 1-0 Crewe Alexandra | Sky Bet League One |
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