| 1 | Sat 7 Aug 2021 | 7 0-1 v Birmingham CitySheffield United 0-1 Birmingham City | Sky Bet Championship |
| 2 | Sat 14 Aug 2021 | 70-0 v Swansea CitySwansea City 0-0 Sheffield United | Sky Bet Championship |
| 3 | Sat 21 Aug 2021 | 71-2 v Huddersfield TownSheffield United 1-2 Huddersfield Town | Sky Bet Championship |
| 4 | Sat 28 Aug 2021 | 70-0 v Luton TownLuton Town 0-0 Sheffield United | Sky Bet Championship |
| 5 | Tue 14 Sep 2021 | 72-2 v Preston North EndSheffield United 2-2 Preston North End | Sky Bet Championship |
| 6 | Tue 21 Sep 2021 | 72-2 v SouthamptonSheffield United 2-2 Southampton | Carabao Cup Third Round |
| 7 | Tue 2 Nov 2021 | 71-1 v Nottingham ForestNottingham Forest 1-1 Sheffield United | Sky Bet Championship |
| 8 | Sat 6 Nov 2021 | 71-3 v Blackburn RoversBlackburn Rovers 3-1 Sheffield United | Sky Bet Championship |
| 9 | Tue 23 Nov 2021 | 7 1-0 v ReadingReading 0-1 Sheffield United | Sky Bet Championship |
| 10 | Sun 28 Nov 2021 | 72-0 v Bristol CitySheffield United 2-0 Bristol City | Sky Bet Championship |
| 11 | Sat 15 Jan 2022 | 70-2 v Derby CountyDerby County 2-0 Sheffield United | Sky Bet Championship |
| 12 | Tue 18 Jan 2022 | 72-2 v Preston North EndPreston North End 2-2 Sheffield United | Sky Bet Championship |
| 13 | Sat 22 Jan 2022 | 72-0 v Luton TownSheffield United 2-0 Luton Town | Sky Bet Championship |
| 14 | Sat 29 Jan 2022 | 72-0 v Peterborough UnitedPeterborough United 0-2 Sheffield United | Sky Bet Championship |
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