| 1 | Fri 13 Aug 2021 | 201-0 v Go Ahead EaglesGo Ahead Eagles 0-1 sc Heerenveen | Dutch Eredivisie |
| 2 | Sat 21 Aug 2021 | 203-2 v RKC Waalwijksc Heerenveen 3-2 RKC Waalwijk | Dutch Eredivisie |
| 3 | Sun 29 Aug 2021 | 201-3 v AZ Alkmaarsc Heerenveen 1-3 AZ Alkmaar | Dutch Eredivisie |
| 4 | Sun 12 Sep 2021 | 201-1 v FC GroningenFC Groningen 1-1 sc Heerenveen | Dutch Eredivisie |
| 5 | Sat 18 Sep 2021 | 201-0 v Fortuna Sittardsc Heerenveen 1-0 Fortuna Sittard | Dutch Eredivisie |
| 6 | Wed 22 Sep 2021 | 201-3 v FeyenoordFeyenoord 3-1 sc Heerenveen | Dutch Eredivisie |
| 7 | Sun 26 Sep 2021 | 20 2-3 v FC Twentesc Heerenveen 2-3 FC Twente | Dutch Eredivisie |
| 8 | Sat 2 Oct 2021 | 201-0 v PEC ZwollePEC Zwolle 0-1 sc Heerenveen | Dutch Eredivisie |
| 9 | Sat 16 Oct 2021 | 200-2 v Ajaxsc Heerenveen 0-2 Ajax | Dutch Eredivisie |
| 10 | Sat 23 Oct 2021 | 201-2 v FC UtrechtFC Utrecht 2-1 sc Heerenveen | Dutch Eredivisie |
| 11 | Sat 30 Oct 2021 | 201-2 v Vitessesc Heerenveen 1-2 Vitesse | Dutch Eredivisie |
| 12 | Sat 6 Nov 2021 | 201-1 v NEC NijmegenNEC Nijmegen 1-1 sc Heerenveen | Dutch Eredivisie |
| 13 | Sun 21 Nov 2021 | 202-1 v Willem IIsc Heerenveen 2-1 Willem II | Dutch Eredivisie |
| 14 | Sun 28 Nov 2021 | 201-1 v PSV Eindhovensc Heerenveen 1-1 PSV Eindhoven | Dutch Eredivisie |
| 15 | Sat 4 Dec 2021 | 201-0 v Heracles AlmeloHeracles Almelo 0-1 sc Heerenveen | Dutch Eredivisie |
| 16 | Sat 11 Dec 2021 | 200-0 v Sparta Rotterdamsc Heerenveen 0-0 Sparta Rotterdam | Dutch Eredivisie |
| 17 | Wed 22 Dec 2021 | 200-3 v Feyenoordsc Heerenveen 0-3 Feyenoord | Dutch Eredivisie |
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