| 1 | Thu 7 Aug | 23 3-0 v LarneLarne 0-3 Santa Clara | UEFA Europa Conference League Third Qualifying Round |
| 2 | Sun 10 Aug | 230-3 v FamalicãoFamalicão 3-0 Santa Clara | Portuguese Primeira Liga |
| 3 | Sun 17 Aug | 230-1 v MoreirenseSanta Clara 0-1 Moreirense | Portuguese Primeira Liga |
| 4 | Thu 21 Aug | 231-2 v Shamrock RoversSanta Clara 1-2 Shamrock Rovers | UEFA Europa Conference League |
| 5 | Thu 28 Aug | 230-0 v Shamrock RoversShamrock Rovers 0-0 Santa Clara | UEFA Europa Conference League |
| 6 | Sun 31 Aug | 23 0-0 v Estrela da AmadoraSanta Clara 0-0 Estrela da Amadora | Portuguese Primeira Liga |
| 7 | Sat 6 Sep | 231-0 v Estoril PraiaEstoril Praia 0-1 Santa Clara | Portuguese Primeira Liga |
| 8 | Fri 12 Sep | 231-1 v BenficaBenfica 1-1 Santa Clara | Portuguese Primeira Liga |
| 9 | Sat 20 Sep | 232-1 v AlvercaSanta Clara 2-1 Alverca | Portuguese Primeira Liga |
| 10 | Sat 27 Sep | 231-2 v TondelaSanta Clara 1-2 Tondela | Portuguese Primeira Liga |
| 11 | Sat 4 Oct | 23 1-2 v Vitória GuimarãesVitória Guimarães 2-1 Santa Clara | Portuguese Primeira Liga |
| 12 | Sat 25 Oct | 232-0 v AVS Futebol SADSanta Clara 2-0 AVS Futebol SAD | Portuguese Primeira Liga |
| 13 | Mon 3 Nov | 230-1 v Gil VicenteGil Vicente 1-0 Santa Clara | Portuguese Primeira Liga |
| 14 | Sat 8 Nov | 23 1-2 v Sporting CPSanta Clara 1-2 Sporting CP | Portuguese Primeira Liga |
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