| 1 | Sun 15 Aug 2021 | 192-2 v LensLens 2-2 Saint Étienne | French Ligue 1 |
| 2 | Sat 21 Aug 2021 | 191-1 v LilleSaint Étienne 1-1 Lille | French Ligue 1 |
| 3 | Sat 28 Aug 2021 | 191-3 v MarseilleMarseille 3-1 Saint Étienne | French Ligue 1 |
| 4 | Sun 12 Sep 2021 | 19 0-2 v MontpellierMontpellier 2-0 Saint Étienne | French Ligue 1 |
| 5 | Sat 18 Sep 2021 | 191-2 v BordeauxSaint Étienne 1-2 Bordeaux | French Ligue 1 |
| 6 | Wed 22 Sep 2021 | 191-3 v MonacoMonaco 3-1 Saint Étienne | French Ligue 1 |
| 7 | Sat 25 Sep 2021 | 190-3 v NiceSaint Étienne 0-3 Nice | French Ligue 1 |
| 8 | Sun 3 Oct 2021 | 191-1 v LyonSaint Étienne 1-1 Lyon | French Ligue 1 |
| 9 | Sun 17 Oct 2021 | 191-5 v StrasbourgStrasbourg 5-1 Saint Étienne | French Ligue 1 |
| 10 | Fri 22 Oct 2021 | 192-2 v AngersSaint Étienne 2-2 Angers | French Ligue 1 |
| 11 | Sat 30 Oct 2021 | 191-1 v MetzMetz 1-1 Saint Étienne | French Ligue 1 |
| 12 | Sat 11 Dec 2021 | 190-2 v ReimsReims 2-0 Saint Étienne | French Ligue 1 |
| 13 | Wed 22 Dec 2021 | 190-1 v NantesSaint Étienne 0-1 Nantes | French Ligue 1 |
| 14 | Fri 8 Apr 2022 | 19 2-6 v LorientLorient 6-2 Saint Étienne | French Ligue 1 |
| 15 | Wed 20 Apr 2022 | 19 2-2 v BordeauxBordeaux 2-2 Saint Étienne | French Ligue 1 |
| 16 | Sat 30 Apr 2022 | 190-2 v RennesRennes 2-0 Saint Étienne | French Ligue 1 |
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