| 1 | Sat 15 Jan 2022 | 311-2 v LensSaint Étienne 1-2 Lens | French Ligue 1 |
| 2 | Fri 21 Jan 2022 | 31 0-1 v LyonLyon 1-0 Saint Étienne | French Ligue 1 |
| 3 | Wed 26 Jan 2022 | 311-0 v AngersAngers 0-1 Saint Étienne | French Ligue 1 |
| 4 | Sat 5 Feb 2022 | 93-1 v MontpellierSaint Étienne 3-1 Montpellier | French Ligue 1 |
| 5 | Sun 13 Feb 2022 | 92-1 v ClermontClermont 1-2 Saint Étienne | French Ligue 1 |
| 6 | Sun 20 Feb 2022 | 92-2 v StrasbourgSaint Étienne 2-2 Strasbourg | French Ligue 1 |
| 7 | Sat 26 Feb 2022 | 91-3 v Paris St GermainParis St Germain 3-1 Saint Étienne | French Ligue 1 |
| 8 | Sun 6 Mar 2022 | 91-0 v MetzSaint Étienne 1-0 Metz | French Ligue 1 |
| 9 | Fri 11 Mar 2022 | 90-0 v LilleLille 0-0 Saint Étienne | French Ligue 1 |
| 10 | Fri 18 Mar 2022 | 91-1 v TroyesSaint Étienne 1-1 Troyes | French Ligue 1 |
| 11 | Sun 3 Apr 2022 | 9 2-4 v MarseilleSaint Étienne 2-4 Marseille | French Ligue 1 |
| 12 | Fri 8 Apr 2022 | 92-6 v LorientLorient 6-2 Saint Étienne | French Ligue 1 |
| 13 | Sat 16 Apr 2022 | 92-1 v BrestSaint Étienne 2-1 Brest | French Ligue 1 |
| 14 | Wed 20 Apr 2022 | 92-2 v BordeauxBordeaux 2-2 Saint Étienne | French Ligue 1 |
| 15 | Sat 30 Apr 2022 | 90-2 v RennesRennes 2-0 Saint Étienne | French Ligue 1 |
| 16 | Wed 11 May 2022 | 92-4 v NiceNice 4-2 Saint Étienne | French Ligue 1 |
| 17 | Sat 21 May 2022 | 91-1 v NantesNantes 1-1 Saint Étienne | French Ligue 1 |
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