| 1 | Sat 27 Jul | 51-0 v Sint-Truidense VVRSC Anderlecht 1-0 Sint-Truidense VV | Belgian First Division A |
| 2 | Sun 4 Aug | 52-1 v Royal AntwerpRoyal Antwerp 1-2 RSC Anderlecht | Belgian First Division A |
| 3 | Sat 10 Aug | 51-1 v Oud-Heverlee LeuvenRSC Anderlecht 1-1 Oud-Heverlee Leuven | Belgian First Division A |
| 4 | Thu 29 Aug | 51-0 v Dinamo MinskRSC Anderlecht 1-0 Dinamo Minsk | UEFA Europa League Play-off |
| 5 | Sat 21 Sep | 5 0-0 v Sporting de CharleroiRSC Anderlecht 0-0 Sporting de Charleroi | Belgian First Division A |
| 6 | Wed 25 Sep | 52-1 v Ferencvárosi TCRSC Anderlecht 2-1 Ferencvárosi TC | UEFA Europa League Matchday 1 |
| 7 | Sat 28 Sep | 5 1-1 v FCV Dender EHFCV Dender EH 1-1 RSC Anderlecht | Belgian First Division A |
| 8 | Thu 3 Oct | 52-1 v Real SociedadReal Sociedad 1-2 RSC Anderlecht | UEFA Europa League Matchday 2 |
| 9 | Sun 6 Oct | 53-0 v Standard LiègeRSC Anderlecht 3-0 Standard Liège | Belgian First Division A |
| 10 | Fri 18 Oct | 51-2 v Germinal BeerschotGerminal Beerschot 2-1 RSC Anderlecht | Belgian First Division A |
| 11 | Thu 24 Oct | 52-0 v LudogoretsRSC Anderlecht 2-0 Ludogorets | UEFA Europa League Matchday 3 |
| 12 | Sun 27 Oct | 51-2 v Club BruggeClub Brugge 2-1 RSC Anderlecht | Belgian First Division A |
| 13 | Sun 3 Nov | 54-0 v KV KortrijkRSC Anderlecht 4-0 KV Kortrijk | Belgian First Division A |
| 14 | Thu 7 Nov | 51-1 v Rīgas FSRīgas FS 1-1 RSC Anderlecht | UEFA Europa League Matchday 4 |
| 15 | Sun 10 Nov | 5 5-0 v Cercle BruggeCercle Brugge 0-5 RSC Anderlecht | Belgian First Division A |
| 16 | Sun 24 Nov | 56-0 v KAA GentRSC Anderlecht 6-0 KAA Gent | Belgian First Division A |
| 17 | Thu 28 Nov | 5 2-2 v FC PortoRSC Anderlecht 2-2 FC Porto | UEFA Europa League Matchday 5 |
| 18 | Sun 1 Dec | 50-0 v Oud-Heverlee LeuvenOud-Heverlee Leuven 0-0 RSC Anderlecht | Belgian First Division A |
| 19 | Sun 8 Dec | 52-1 v Germinal BeerschotRSC Anderlecht 2-1 Germinal Beerschot | Belgian First Division A |
| 20 | Thu 12 Dec | 52-1 v Slavia PragueSlavia Prague 1-2 RSC Anderlecht | UEFA Europa League Matchday 6 |
| 21 | Sun 15 Dec | 5 2-0 v Sint-Truidense VVSint-Truidense VV 0-2 RSC Anderlecht | Belgian First Division A |
| 22 | Sun 22 Dec | 50-2 v KRC GenkKRC Genk 2-0 RSC Anderlecht | Belgian First Division A |
| 23 | Fri 27 Dec | 52-3 v FCV Dender EHRSC Anderlecht 2-3 FCV Dender EH | Belgian First Division A |
| 24 | Sun 19 Jan | 52-0 v KV KortrijkKV Kortrijk 0-2 RSC Anderlecht | Belgian First Division A |
| 25 | Thu 23 Jan | 50-2 v Viktoria PlzenViktoria Plzen 2-0 RSC Anderlecht | UEFA Europa League Matchday 7 |
| 26 | Sun 26 Jan | 54-1 v MechelenRSC Anderlecht 4-1 Mechelen | Belgian First Division A |
| 27 | Sun 2 Feb | 5 0-1 v KAA GentKAA Gent 1-0 RSC Anderlecht | Belgian First Division A |
| 28 | Sun 16 Feb | 51-0 v Sporting de CharleroiSporting de Charleroi 0-1 RSC Anderlecht | Belgian First Division A |
| 29 | Thu 20 Feb | 52-2 v FenerbahçeRSC Anderlecht 2-2 Fenerbahçe | UEFA Europa League Play-off Knockout Round |
| 30 | Sun 23 Feb | 50-2 v Union Saint-GilloiseRSC Anderlecht 0-2 Union Saint-Gilloise | Belgian First Division A |
| 31 | Sun 16 Mar | 53-0 v Cercle BruggeRSC Anderlecht 3-0 Cercle Brugge | Belgian First Division A |
| 32 | Sun 30 Mar | 50-2 v Club BruggeClub Brugge 2-0 RSC Anderlecht | Belgian First Division A Play-off |
| 33 | Sun 20 Apr | 50-0 v Royal AntwerpRSC Anderlecht 0-0 Royal Antwerp | Belgian First Division A Play-off |
| 34 | Wed 23 Apr | 55-0 v KAA GentRSC Anderlecht 5-0 KAA Gent | Belgian First Division A Play-off |
| 35 | Sun 27 Apr | 51-0 v KAA GentKAA Gent 0-1 RSC Anderlecht | Belgian First Division A Play-off |
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