| 1 | Sat 10 Aug | 71-1 v Oud-Heverlee LeuvenRSC Anderlecht 1-1 Oud-Heverlee Leuven | Belgian First Division A |
| 2 | Sat 17 Aug | 7 3-1 v MechelenMechelen 1-3 RSC Anderlecht | Belgian First Division A |
| 3 | Thu 29 Aug | 71-0 v Dinamo MinskRSC Anderlecht 1-0 Dinamo Minsk | UEFA Europa League Play-off |
| 4 | Sun 1 Sep | 70-0 v Union Saint-GilloiseUnion Saint-Gilloise 0-0 RSC Anderlecht | Belgian First Division A |
| 5 | Sat 14 Sep | 72-2 v KVC WesterloRSC Anderlecht 2-2 KVC Westerlo | Belgian First Division A |
| 6 | Tue 17 Sep | 70-2 v KRC GenkRSC Anderlecht 0-2 KRC Genk | Belgian First Division A |
| 7 | Sat 21 Sep | 70-0 v Sporting de CharleroiRSC Anderlecht 0-0 Sporting de Charleroi | Belgian First Division A |
| 8 | Wed 25 Sep | 72-1 v Ferencvárosi TCRSC Anderlecht 2-1 Ferencvárosi TC | UEFA Europa League Matchday 1 |
| 9 | Fri 18 Oct | 71-2 v Germinal BeerschotGerminal Beerschot 2-1 RSC Anderlecht | Belgian First Division A |
| 10 | Sun 27 Oct | 71-2 v Club BruggeClub Brugge 2-1 RSC Anderlecht | Belgian First Division A |
| 11 | Sun 3 Nov | 74-0 v KV KortrijkRSC Anderlecht 4-0 KV Kortrijk | Belgian First Division A |
| 12 | Thu 7 Nov | 71-1 v Rīgas FSRīgas FS 1-1 RSC Anderlecht | UEFA Europa League Matchday 4 |
| 13 | Sun 10 Nov | 75-0 v Cercle BruggeCercle Brugge 0-5 RSC Anderlecht | Belgian First Division A |
| 14 | Sun 24 Nov | 76-0 v KAA GentRSC Anderlecht 6-0 KAA Gent | Belgian First Division A |
| 15 | Thu 28 Nov | 72-2 v FC PortoRSC Anderlecht 2-2 FC Porto | UEFA Europa League Matchday 5 |
| 16 | Sun 1 Dec | 70-0 v Oud-Heverlee LeuvenOud-Heverlee Leuven 0-0 RSC Anderlecht | Belgian First Division A |
| 17 | Sun 8 Dec | 72-1 v Germinal BeerschotRSC Anderlecht 2-1 Germinal Beerschot | Belgian First Division A |
| 18 | Thu 12 Dec | 72-1 v Slavia PragueSlavia Prague 1-2 RSC Anderlecht | UEFA Europa League Matchday 6 |
| 19 | Sun 15 Dec | 72-0 v Sint-Truidense VVSint-Truidense VV 0-2 RSC Anderlecht | Belgian First Division A |
| 20 | Sun 22 Dec | 70-2 v KRC GenkKRC Genk 2-0 RSC Anderlecht | Belgian First Division A |
| 21 | Fri 27 Dec | 72-3 v FCV Dender EHRSC Anderlecht 2-3 FCV Dender EH | Belgian First Division A |
| 22 | Sun 12 Jan | 70-3 v Club BruggeRSC Anderlecht 0-3 Club Brugge | Belgian First Division A |
| 23 | Thu 23 Jan | 70-2 v Viktoria PlzenViktoria Plzen 2-0 RSC Anderlecht | UEFA Europa League Matchday 7 |
| 24 | Sun 26 Jan | 74-1 v MechelenRSC Anderlecht 4-1 Mechelen | Belgian First Division A |
| 25 | Thu 30 Jan | 73-4 v 1899 HoffenheimRSC Anderlecht 3-4 1899 Hoffenheim | UEFA Europa League Matchday 8 |
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