| 1 | Sun 25 Oct 2020 | 170-2 v AlavésReal Valladolid 0-2 Alavés | Spanish La Liga |
| 2 | Sat 5 Dec 2020 | 17 0-2 v Atlético MadridAtlético Madrid 2-0 Real Valladolid | Spanish La Liga |
| 3 | Fri 11 Dec 2020 | 17 3-2 v OsasunaReal Valladolid 3-2 Osasuna | Spanish La Liga |
| 4 | Sat 19 Dec 2020 | 171-1 v SevillaSevilla 1-1 Real Valladolid | Spanish La Liga |
| 5 | Tue 22 Dec 2020 | 170-3 v BarcelonaReal Valladolid 0-3 Barcelona | Spanish La Liga |
| 6 | Tue 29 Dec 2020 | 17 0-0 v CádizCádiz 0-0 Real Valladolid | Spanish La Liga |
| 7 | Sat 2 Jan 2021 | 171-0 v GetafeGetafe 0-1 Real Valladolid | Spanish La Liga |
| 8 | Sun 10 Jan 2021 | 170-1 v ValenciaReal Valladolid 0-1 Valencia | Spanish La Liga |
| 9 | Tue 19 Jan 2021 | 17 2-2 v ElcheReal Valladolid 2-2 Elche | Spanish La Liga |
| 10 | Fri 5 Feb 2021 | 170-1 v AlavésAlavés 1-0 Real Valladolid | Spanish La Liga |
| 11 | Sat 13 Feb 2021 | 171-1 v EibarEibar 1-1 Real Valladolid | Spanish La Liga |
| 12 | Sat 20 Feb 2021 | 170-1 v Real MadridReal Valladolid 0-1 Real Madrid | Spanish La Liga |
| 13 | Sun 28 Feb 2021 | 171-1 v Celta VigoCelta Vigo 1-1 Real Valladolid | Spanish La Liga |
| 14 | Sat 6 Mar 2021 | 172-1 v GetafeReal Valladolid 2-1 Getafe | Spanish La Liga |
| 15 | Sat 13 Mar 2021 | 170-0 v OsasunaOsasuna 0-0 Real Valladolid | Spanish La Liga |
| 16 | Sat 20 Mar 2021 | 17 1-1 v SevillaReal Valladolid 1-1 Sevilla | Spanish La Liga |
| 17 | Mon 5 Apr 2021 | 170-1 v BarcelonaBarcelona 1-0 Real Valladolid | Spanish La Liga |
| 18 | Sun 11 Apr 2021 | 171-2 v GranadaReal Valladolid 1-2 Granada | Spanish La Liga |
| 19 | Wed 21 Apr 2021 | 171-1 v ElcheElche 1-1 Real Valladolid | Spanish La Liga |
| 20 | Sat 24 Apr 2021 | 171-1 v CádizReal Valladolid 1-1 Cádiz | Spanish La Liga |
| 21 | Wed 28 Apr 2021 | 172-2 v Athletic BilbaoAthletic Bilbao 2-2 Real Valladolid | Spanish La Liga |
| 22 | Sun 2 May 2021 | 171-1 v Real BetisReal Valladolid 1-1 Real Betis | Spanish La Liga |
| 23 | Sun 9 May 2021 | 170-3 v ValenciaValencia 3-0 Real Valladolid | Spanish La Liga |
| 24 | Thu 13 May 2021 | 170-2 v VillarrealReal Valladolid 0-2 Villarreal | Spanish La Liga |
| 25 | Sat 22 May 2021 | 171-2 v Atlético MadridReal Valladolid 1-2 Atlético Madrid | Spanish La Liga |
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