| 1 | Fri 29 Jan 2021 | 31-3 v HuescaReal Valladolid 1-3 Huesca | Spanish La Liga |
| 2 | Fri 5 Feb 2021 | 30-1 v AlavésAlavés 1-0 Real Valladolid | Spanish La Liga |
| 3 | Sat 13 Feb 2021 | 31-1 v EibarEibar 1-1 Real Valladolid | Spanish La Liga |
| 4 | Sat 20 Feb 2021 | 30-1 v Real MadridReal Valladolid 0-1 Real Madrid | Spanish La Liga |
| 5 | Sun 28 Feb 2021 | 31-1 v Celta VigoCelta Vigo 1-1 Real Valladolid | Spanish La Liga |
| 6 | Sat 6 Mar 2021 | 32-1 v GetafeReal Valladolid 2-1 Getafe | Spanish La Liga |
| 7 | Sat 13 Mar 2021 | 30-0 v OsasunaOsasuna 0-0 Real Valladolid | Spanish La Liga |
| 8 | Sat 20 Mar 2021 | 31-1 v SevillaReal Valladolid 1-1 Sevilla | Spanish La Liga |
| 9 | Mon 5 Apr 2021 | 30-1 v BarcelonaBarcelona 1-0 Real Valladolid | Spanish La Liga |
| 10 | Sun 11 Apr 2021 | 31-2 v GranadaReal Valladolid 1-2 Granada | Spanish La Liga |
| 11 | Wed 21 Apr 2021 | 3 1-1 v ElcheElche 1-1 Real Valladolid | Spanish La Liga |
| 12 | Sat 24 Apr 2021 | 31-1 v CádizReal Valladolid 1-1 Cádiz | Spanish La Liga |
| 13 | Sun 9 May 2021 | 30-3 v ValenciaValencia 3-0 Real Valladolid | Spanish La Liga |
| 14 | Sun 16 May 2021 | 31-4 v Real SociedadReal Sociedad 4-1 Real Valladolid | Spanish La Liga |
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