| 1 | Mon 2 Nov 2020 | 10-2 v VillarrealVillarreal 2-0 Real Valladolid | Spanish La Liga |
| 2 | Sun 8 Nov 2020 | 1 2-1 v Athletic BilbaoReal Valladolid 2-1 Athletic Bilbao | Spanish La Liga |
| 3 | Sun 22 Nov 2020 | 13-1 v GranadaGranada 1-3 Real Valladolid | Spanish La Liga |
| 4 | Fri 27 Nov 2020 | 11-1 v LevanteReal Valladolid 1-1 Levante | Spanish La Liga |
| 5 | Sat 5 Dec 2020 | 10-2 v Atlético MadridAtlético Madrid 2-0 Real Valladolid | Spanish La Liga |
| 6 | Fri 11 Dec 2020 | 13-2 v OsasunaReal Valladolid 3-2 Osasuna | Spanish La Liga |
| 7 | Sat 19 Dec 2020 | 11-1 v SevillaSevilla 1-1 Real Valladolid | Spanish La Liga |
| 8 | Tue 22 Dec 2020 | 10-3 v BarcelonaReal Valladolid 0-3 Barcelona | Spanish La Liga |
| 9 | Tue 29 Dec 2020 | 10-0 v CádizCádiz 0-0 Real Valladolid | Spanish La Liga |
| 10 | Sat 2 Jan 2021 | 11-0 v GetafeGetafe 0-1 Real Valladolid | Spanish La Liga |
| 11 | Sun 10 Jan 2021 | 10-1 v ValenciaReal Valladolid 0-1 Valencia | Spanish La Liga |
| 12 | Tue 19 Jan 2021 | 12-2 v ElcheReal Valladolid 2-2 Elche | Spanish La Liga |
| 13 | Fri 22 Jan 2021 | 12-2 v LevanteLevante 2-2 Real Valladolid | Spanish La Liga |
| 14 | Fri 29 Jan 2021 | 11-3 v HuescaReal Valladolid 1-3 Huesca | Spanish La Liga |
| 15 | Fri 5 Feb 2021 | 10-1 v AlavésAlavés 1-0 Real Valladolid | Spanish La Liga |
| 16 | Sat 13 Feb 2021 | 11-1 v EibarEibar 1-1 Real Valladolid | Spanish La Liga |
| 17 | Sat 20 Feb 2021 | 10-1 v Real MadridReal Valladolid 0-1 Real Madrid | Spanish La Liga |
| 18 | Mon 5 Apr 2021 | 1 0-1 v BarcelonaBarcelona 1-0 Real Valladolid | Spanish La Liga |
| 19 | Sun 11 Apr 2021 | 1 1-2 v GranadaReal Valladolid 1-2 Granada | Spanish La Liga |
| 20 | Wed 21 Apr 2021 | 11-1 v ElcheElche 1-1 Real Valladolid | Spanish La Liga |
| 21 | Wed 28 Apr 2021 | 12-2 v Athletic BilbaoAthletic Bilbao 2-2 Real Valladolid | Spanish La Liga |
| 22 | Sun 9 May 2021 | 10-3 v ValenciaValencia 3-0 Real Valladolid | Spanish La Liga |
| 23 | Sun 16 May 2021 | 11-4 v Real SociedadReal Sociedad 4-1 Real Valladolid | Spanish La Liga |
| 24 | Sat 22 May 2021 | 11-2 v Atlético MadridReal Valladolid 1-2 Atlético Madrid | Spanish La Liga |
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