| 1 | Sun 31 Aug | 181-2 v Athletic BilbaoReal Betis 1-2 Athletic Bilbao | Spanish La Liga |
| 2 | Sun 14 Sep | 182-2 v LevanteLevante 2-2 Real Betis | Spanish La Liga |
| 3 | Thu 23 Oct | 180-0 v KRC GenkKRC Genk 0-0 Real Betis | UEFA Europa League Matchday 3 |
| 4 | Mon 27 Oct | 180-2 v Atlético MadridReal Betis 0-2 Atlético Madrid | Spanish La Liga |
| 5 | Sun 2 Nov | 183-0 v MallorcaReal Betis 3-0 Mallorca | Spanish La Liga |
| 6 | Thu 6 Nov | 182-0 v Olympique LyonnaisReal Betis 2-0 Olympique Lyonnais | UEFA Europa League Matchday 4 |
| 7 | Sun 23 Nov | 18 1-1 v GironaReal Betis 1-1 Girona | Spanish La Liga |
| 8 | Thu 27 Nov | 182-1 v FC UtrechtReal Betis 2-1 FC Utrecht | UEFA Europa League Matchday 5 |
| 9 | Sun 30 Nov | 182-0 v SevillaSevilla 0-2 Real Betis | Spanish La Liga |
| 10 | Sat 6 Dec | 18 3-5 v BarcelonaReal Betis 3-5 Barcelona | Spanish La Liga |
| 11 | Thu 11 Dec | 18 3-1 v Dinamo ZagrebDinamo Zagreb 1-3 Real Betis | UEFA Europa League Matchday 6 |
| 12 | Mon 15 Dec | 180-0 v Rayo VallecanoRayo Vallecano 0-0 Real Betis | Spanish La Liga |
| 13 | Sun 21 Dec | 184-0 v GetafeReal Betis 4-0 Getafe | Spanish La Liga |
| 14 | Sun 4 Jan | 181-5 v Real MadridReal Madrid 5-1 Real Betis | Spanish La Liga |
| 15 | Thu 22 Jan | 180-2 v PAOK FCPAOK FC 2-0 Real Betis | UEFA Europa League Matchday 7 |
| 16 | Sun 25 Jan | 181-2 v AlavésAlavés 2-1 Real Betis | Spanish La Liga |
| 17 | Thu 29 Jan | 182-1 v FeyenoordReal Betis 2-1 Feyenoord | UEFA Europa League Matchday 8 |
| 18 | Sun 1 Feb | 182-1 v ValenciaReal Betis 2-1 Valencia | Spanish La Liga |
| 19 | Sun 8 Feb | 181-0 v Atlético MadridAtlético Madrid 0-1 Real Betis | Spanish La Liga |
| 20 | Sun 15 Feb | 182-1 v MallorcaMallorca 1-2 Real Betis | Spanish La Liga |
| 21 | Sat 21 Feb | 18 1-1 v Rayo VallecanoReal Betis 1-1 Rayo Vallecano | Spanish La Liga |
| 22 | Sun 8 Mar | 180-2 v GetafeGetafe 2-0 Real Betis | Spanish La Liga |
| 23 | Thu 12 Mar | 180-1 v PanathinaikosPanathinaikos 1-0 Real Betis | UEFA Europa League Round of 16 |
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