| 1 | Sun 14 Sep | 72-2 v LevanteLevante 2-2 Real Betis | Spanish La Liga |
| 2 | Fri 19 Sep | 73-1 v Real SociedadReal Betis 3-1 Real Sociedad | Spanish La Liga |
| 3 | Wed 24 Sep | 72-2 v Nottingham ForestReal Betis 2-2 Nottingham Forest | UEFA Europa League Matchday 1 |
| 4 | Sun 28 Sep | 72-0 v OsasunaReal Betis 2-0 Osasuna | Spanish La Liga |
| 5 | Sun 5 Oct | 7 2-1 v EspanyolEspanyol 1-2 Real Betis | Spanish La Liga |
| 6 | Sat 18 Oct | 72-2 v VillarrealVillarreal 2-2 Real Betis | Spanish La Liga |
| 7 | Thu 23 Oct | 7 0-0 v KRC GenkKRC Genk 0-0 Real Betis | UEFA Europa League Matchday 3 |
| 8 | Mon 27 Oct | 70-2 v Atlético MadridReal Betis 0-2 Atlético Madrid | Spanish La Liga |
| 9 | Sun 2 Nov | 73-0 v MallorcaReal Betis 3-0 Mallorca | Spanish La Liga |
| 10 | Thu 6 Nov | 72-0 v Olympique LyonnaisReal Betis 2-0 Olympique Lyonnais | UEFA Europa League Matchday 4 |
| 11 | Sun 9 Nov | 71-1 v ValenciaValencia 1-1 Real Betis | Spanish La Liga |
| 12 | Sun 23 Nov | 7 1-1 v GironaReal Betis 1-1 Girona | Spanish La Liga |
| 13 | Thu 27 Nov | 72-1 v FC UtrechtReal Betis 2-1 FC Utrecht | UEFA Europa League Matchday 5 |
| 14 | Sat 6 Dec | 73-5 v BarcelonaReal Betis 3-5 Barcelona | Spanish La Liga |
| 15 | Thu 11 Dec | 73-1 v Dinamo ZagrebDinamo Zagreb 1-3 Real Betis | UEFA Europa League Matchday 6 |
| 16 | Mon 15 Dec | 70-0 v Rayo VallecanoRayo Vallecano 0-0 Real Betis | Spanish La Liga |
| 17 | Sun 21 Dec | 74-0 v GetafeReal Betis 4-0 Getafe | Spanish La Liga |
| 18 | Sun 4 Jan | 71-5 v Real MadridReal Madrid 5-1 Real Betis | Spanish La Liga |
| 19 | Sat 10 Jan | 71-1 v Real OviedoReal Oviedo 1-1 Real Betis | Spanish La Liga |
| 20 | Sat 17 Jan | 72-0 v VillarrealReal Betis 2-0 Villarreal | Spanish La Liga |
| 21 | Sun 25 Jan | 71-2 v AlavésAlavés 2-1 Real Betis | Spanish La Liga |
| 22 | Thu 29 Jan | 72-1 v FeyenoordReal Betis 2-1 Feyenoord | UEFA Europa League Matchday 8 |
| 23 | Sun 1 Feb | 72-1 v ValenciaReal Betis 2-1 Valencia | Spanish La Liga |
| 24 | Sun 8 Feb | 71-0 v Atlético MadridAtlético Madrid 0-1 Real Betis | Spanish La Liga |
| 25 | Sun 15 Feb | 72-1 v MallorcaMallorca 1-2 Real Betis | Spanish La Liga |
| 26 | Sat 21 Feb | 71-1 v Rayo VallecanoReal Betis 1-1 Rayo Vallecano | Spanish La Liga |
| 27 | Sun 1 Mar | 7 2-2 v SevillaReal Betis 2-2 Sevilla | Spanish La Liga |
| 28 | Sun 8 Mar | 7 0-2 v GetafeGetafe 2-0 Real Betis | Spanish La Liga |
| 29 | Thu 12 Mar | 70-1 v PanathinaikosPanathinaikos 1-0 Real Betis | UEFA Europa League Round of 16 |
| 30 | Sun 15 Mar | 7 1-1 v Celta VigoReal Betis 1-1 Celta Vigo | Spanish La Liga |
| 31 | Thu 19 Mar | 74-0 v PanathinaikosReal Betis 4-0 Panathinaikos | UEFA Europa League Round of 16 |
| 32 | Sun 22 Mar | 71-2 v Athletic BilbaoAthletic Bilbao 2-1 Real Betis | Spanish La Liga |
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