| 1 | Mon 18 Aug | 241-1 v ElcheElche 1-1 Real Betis | Spanish La Liga |
| 2 | Fri 22 Aug | 241-0 v AlavésReal Betis 1-0 Alavés | Spanish La Liga |
| 3 | Wed 27 Aug | 241-1 v Celta VigoCelta Vigo 1-1 Real Betis | Spanish La Liga |
| 4 | Sun 28 Sep | 242-0 v OsasunaReal Betis 2-0 Osasuna | Spanish La Liga |
| 5 | Thu 2 Oct | 24 2-0 v LudogoretsLudogorets 0-2 Real Betis | UEFA Europa League Matchday 2 |
| 6 | Sun 5 Oct | 242-1 v EspanyolEspanyol 1-2 Real Betis | Spanish La Liga |
| 7 | Sat 18 Oct | 242-2 v VillarrealVillarreal 2-2 Real Betis | Spanish La Liga |
| 8 | Thu 23 Oct | 240-0 v KRC GenkKRC Genk 0-0 Real Betis | UEFA Europa League Matchday 3 |
| 9 | Mon 27 Oct | 240-2 v Atlético MadridReal Betis 0-2 Atlético Madrid | Spanish La Liga |
| 10 | Sun 2 Nov | 243-0 v MallorcaReal Betis 3-0 Mallorca | Spanish La Liga |
| 11 | Thu 6 Nov | 24 2-0 v Olympique LyonnaisReal Betis 2-0 Olympique Lyonnais | UEFA Europa League Matchday 4 |
| 12 | Sun 23 Nov | 241-1 v GironaReal Betis 1-1 Girona | Spanish La Liga |
| 13 | Sun 30 Nov | 24 2-0 v SevillaSevilla 0-2 Real Betis | Spanish La Liga |
| 14 | Sat 6 Dec | 24 3-5 v BarcelonaReal Betis 3-5 Barcelona | Spanish La Liga |
| 15 | Thu 11 Dec | 243-1 v Dinamo ZagrebDinamo Zagreb 1-3 Real Betis | UEFA Europa League Matchday 6 |
| 16 | Mon 15 Dec | 240-0 v Rayo VallecanoRayo Vallecano 0-0 Real Betis | Spanish La Liga |
| 17 | Sun 21 Dec | 244-0 v GetafeReal Betis 4-0 Getafe | Spanish La Liga |
| 18 | Sun 4 Jan | 241-5 v Real MadridReal Madrid 5-1 Real Betis | Spanish La Liga |
| 19 | Sat 10 Jan | 241-1 v Real OviedoReal Oviedo 1-1 Real Betis | Spanish La Liga |
| 20 | Sat 17 Jan | 242-0 v VillarrealReal Betis 2-0 Villarreal | Spanish La Liga |
| 21 | Thu 22 Jan | 240-2 v PAOK FCPAOK FC 2-0 Real Betis | UEFA Europa League Matchday 7 |
| 22 | Thu 29 Jan | 242-1 v FeyenoordReal Betis 2-1 Feyenoord | UEFA Europa League Matchday 8 |
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