| 1 | Sun 20 Sep 2020 | 232-0 v Real ValladolidReal Betis 2-0 Real Valladolid | Spanish La Liga |
| 2 | Sat 26 Sep 2020 | 23 2-3 v Real MadridReal Betis 2-3 Real Madrid | Spanish La Liga |
| 3 | Tue 29 Sep 2020 | 23 0-3 v GetafeGetafe 3-0 Real Betis | Spanish La Liga |
| 4 | Sat 24 Oct 2020 | 230-2 v Atlético MadridAtlético Madrid 2-0 Real Betis | Spanish La Liga |
| 5 | Sun 1 Nov 2020 | 233-1 v ElcheReal Betis 3-1 Elche | Spanish La Liga |
| 6 | Sat 7 Nov 2020 | 23 2-5 v BarcelonaBarcelona 5-2 Real Betis | Spanish La Liga |
| 7 | Sun 20 Dec 2020 | 230-2 v GranadaGranada 2-0 Real Betis | Spanish La Liga |
| 8 | Wed 23 Dec 2020 | 231-0 v CádizReal Betis 1-0 Cádiz | Spanish La Liga |
| 9 | Tue 29 Dec 2020 | 23 3-4 v LevanteLevante 4-3 Real Betis | Spanish La Liga |
| 10 | Sat 2 Jan 2021 | 231-1 v SevillaReal Betis 1-1 Sevilla | Spanish La Liga |
| 11 | Mon 11 Jan 2021 | 232-0 v HuescaHuesca 0-2 Real Betis | Spanish La Liga |
| 12 | Wed 20 Jan 2021 | 232-1 v Celta VigoReal Betis 2-1 Celta Vigo | Spanish La Liga |
| 13 | Sat 23 Jan 2021 | 232-2 v Real SociedadReal Sociedad 2-2 Real Betis | Spanish La Liga |
| 14 | Mon 1 Feb 2021 | 231-0 v OsasunaReal Betis 1-0 Osasuna | Spanish La Liga |
| 15 | Sun 7 Feb 2021 | 232-3 v BarcelonaReal Betis 2-3 Barcelona | Spanish La Liga |
| 16 | Sun 14 Feb 2021 | 232-1 v VillarrealVillarreal 1-2 Real Betis | Spanish La Liga |
| 17 | Fri 19 Feb 2021 | 231-0 v GetafeReal Betis 1-0 Getafe | Spanish La Liga |
| 18 | Sun 28 Feb 2021 | 231-0 v CádizCádiz 0-1 Real Betis | Spanish La Liga |
| 19 | Mon 8 Mar 2021 | 233-2 v AlavésReal Betis 3-2 Alavés | Spanish La Liga |
| 20 | Sun 14 Mar 2021 | 230-1 v SevillaSevilla 1-0 Real Betis | Spanish La Liga |
| 21 | Fri 19 Mar 2021 | 232-0 v LevanteReal Betis 2-0 Levante | Spanish La Liga |
| 22 | Sun 4 Apr 2021 | 231-1 v ElcheElche 1-1 Real Betis | Spanish La Liga |
| 23 | Sun 11 Apr 2021 | 231-1 v Atlético MadridReal Betis 1-1 Atlético Madrid | Spanish La Liga |
| 24 | Sun 18 Apr 2021 | 232-2 v ValenciaReal Betis 2-2 Valencia | Spanish La Liga |
| 25 | Wed 21 Apr 2021 | 230-0 v Athletic BilbaoReal Betis 0-0 Athletic Bilbao | Spanish La Liga |
| 26 | Sat 24 Apr 2021 | 230-0 v Real MadridReal Madrid 0-0 Real Betis | Spanish La Liga |
| 27 | Sun 2 May 2021 | 23 1-1 v Real ValladolidReal Valladolid 1-1 Real Betis | Spanish La Liga |
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