| 1 | Tue 6 Sep 2022 | 371-4 v Shakhtar DonetskRB Leipzig 1-4 Shakhtar Donetsk | UEFA Champions League Group F |
| 2 | Sat 10 Sep 2022 | 373-0 v Borussia DortmundRB Leipzig 3-0 Borussia Dortmund | German Bundesliga |
| 3 | Wed 14 Sep 2022 | 370-2 v Real MadridReal Madrid 2-0 RB Leipzig | UEFA Champions League Group F |
| 4 | Sat 8 Oct 2022 | 371-1 v Mainz 05Mainz 05 1-1 RB Leipzig | German Bundesliga |
| 5 | Tue 11 Oct 2022 | 372-0 v CelticCeltic 0-2 RB Leipzig | UEFA Champions League Group F |
| 6 | Sat 15 Oct 2022 | 373-2 v Hertha BerlinRB Leipzig 3-2 Hertha Berlin | German Bundesliga |
| 7 | Tue 25 Oct 2022 | 373-2 v Real MadridRB Leipzig 3-2 Real Madrid | UEFA Champions League Group F |
| 8 | Sat 29 Oct 2022 | 37 2-0 v Bayer 04 LeverkusenRB Leipzig 2-0 Bayer 04 Leverkusen | German Bundesliga |
| 9 | Wed 2 Nov 2022 | 374-0 v Shakhtar DonetskShakhtar Donetsk 0-4 RB Leipzig | UEFA Champions League Group F |
| 10 | Sat 5 Nov 2022 | 37 3-1 v 1899 Hoffenheim1899 Hoffenheim 1-3 RB Leipzig | German Bundesliga |
| 11 | Wed 9 Nov 2022 | 373-1 v SC FreiburgRB Leipzig 3-1 SC Freiburg | German Bundesliga |
| 12 | Sat 15 Apr 2023 | 373-2 v FC AugsburgRB Leipzig 3-2 FC Augsburg | German Bundesliga |
| 13 | Sat 29 Apr 2023 | 371-0 v 1899 HoffenheimRB Leipzig 1-0 1899 Hoffenheim | German Bundesliga |
| 14 | Sat 20 May 2023 | 373-1 v Bayern MunichBayern Munich 1-3 RB Leipzig | German Bundesliga |
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