| 1 | Sat 10 Aug | 75-1 v RKC WaalwijkPSV Eindhoven 5-1 RKC Waalwijk | Dutch Eredivisie |
| 2 | Sun 18 Aug | 73-1 v Heracles AlmeloHeracles Almelo 1-3 PSV Eindhoven | Dutch Eredivisie |
| 3 | Sat 24 Aug | 77-1 v Almere CityAlmere City 1-7 PSV Eindhoven | Dutch Eredivisie |
| 4 | Sun 1 Sep | 73-0 v Go Ahead EaglesPSV Eindhoven 3-0 Go Ahead Eagles | Dutch Eredivisie |
| 5 | Sat 14 Sep | 72-0 v NEC NijmegenPSV Eindhoven 2-0 NEC Nijmegen | Dutch Eredivisie |
| 6 | Tue 17 Sep | 71-3 v JuventusJuventus 3-1 PSV Eindhoven | UEFA Champions League Matchday 1 |
| 7 | Sun 22 Sep | 7 3-1 v Fortuna SittardFortuna Sittard 1-3 PSV Eindhoven | Dutch Eredivisie |
| 8 | Sat 28 Sep | 72-0 v Willem IIWillem II 0-2 PSV Eindhoven | Dutch Eredivisie |
| 9 | Tue 1 Oct | 7 1-1 v Sporting CPPSV Eindhoven 1-1 Sporting CP | UEFA Champions League Matchday 2 |
| 10 | Sat 5 Oct | 72-1 v Sparta RotterdamPSV Eindhoven 2-1 Sparta Rotterdam | Dutch Eredivisie |
| 11 | Sat 19 Oct | 72-1 v AZ AlkmaarAZ Alkmaar 1-2 PSV Eindhoven | Dutch Eredivisie |
| 12 | Tue 22 Oct | 71-1 v Paris St GermainParis St Germain 1-1 PSV Eindhoven | UEFA Champions League Matchday 3 |
| 13 | Sat 26 Oct | 76-0 v PEC ZwollePSV Eindhoven 6-0 PEC Zwolle | Dutch Eredivisie |
| 14 | Sat 2 Nov | 72-3 v AjaxAjax 3-2 PSV Eindhoven | Dutch Eredivisie |
| 15 | Tue 5 Nov | 74-0 v GironaPSV Eindhoven 4-0 Girona | UEFA Champions League Matchday 4 |
| 16 | Sat 9 Nov | 73-0 v NAC BredaNAC Breda 0-3 PSV Eindhoven | Dutch Eredivisie |
| 17 | Sat 23 Nov | 75-0 v FC GroningenPSV Eindhoven 5-0 FC Groningen | Dutch Eredivisie |
| 18 | Wed 27 Nov | 7 3-2 v Shakhtar DonetskPSV Eindhoven 3-2 Shakhtar Donetsk | UEFA Champions League Matchday 5 |
| 19 | Sun 1 Dec | 75-2 v FC UtrechtFC Utrecht 2-5 PSV Eindhoven | Dutch Eredivisie |
| 20 | Fri 6 Dec | 76-1 v FC TwentePSV Eindhoven 6-1 FC Twente | Dutch Eredivisie |
| 21 | Tue 10 Dec | 7 0-1 v BrestBrest 1-0 PSV Eindhoven | UEFA Champions League Matchday 6 |
| 22 | Sat 14 Dec | 70-1 v sc Heerenveensc Heerenveen 1-0 PSV Eindhoven | Dutch Eredivisie |
| 23 | Sun 22 Dec | 73-0 v FeyenoordPSV Eindhoven 3-0 Feyenoord | Dutch Eredivisie |
| 24 | Sat 11 Jan | 72-2 v AZ AlkmaarPSV Eindhoven 2-2 AZ Alkmaar | Dutch Eredivisie |
| 25 | Sun 30 Mar | 70-2 v AjaxPSV Eindhoven 0-2 Ajax | Dutch Eredivisie |
| 26 | Sat 5 Apr | 73-1 v FC GroningenFC Groningen 1-3 PSV Eindhoven | Dutch Eredivisie |
| 27 | Sat 12 Apr | 75-0 v Almere CityPSV Eindhoven 5-0 Almere City | Dutch Eredivisie |
| 28 | Thu 24 Apr | 73-1 v FC TwenteFC Twente 1-3 PSV Eindhoven | Dutch Eredivisie |
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