| 1 | Sat 9 Aug | 56-1 v Sparta RotterdamPSV Eindhoven 6-1 Sparta Rotterdam | Dutch Eredivisie |
| 2 | Sun 17 Aug | 52-0 v FC TwenteFC Twente 0-2 PSV Eindhoven | Dutch Eredivisie |
| 3 | Sat 23 Aug | 54-2 v FC GroningenPSV Eindhoven 4-2 FC Groningen | Dutch Eredivisie |
| 4 | Sat 30 Aug | 50-2 v TelstarPSV Eindhoven 0-2 Telstar | Dutch Eredivisie |
| 5 | Sat 13 Sep | 5 5-3 v NEC NijmegenNEC Nijmegen 3-5 PSV Eindhoven | Dutch Eredivisie |
| 6 | Tue 16 Sep | 51-3 v Union Saint-GilloisePSV Eindhoven 1-3 Union Saint-Gilloise | UEFA Champions League Matchday 1 |
| 7 | Sun 21 Sep | 5 2-2 v AjaxPSV Eindhoven 2-2 Ajax | Dutch Eredivisie |
| 8 | Sat 27 Sep | 52-1 v Excelsior RotterdamExcelsior Rotterdam 1-2 PSV Eindhoven | Dutch Eredivisie |
| 9 | Wed 1 Oct | 51-1 v Bayer LeverkusenBayer Leverkusen 1-1 PSV Eindhoven | UEFA Champions League Matchday 2 |
| 10 | Sat 18 Oct | 52-1 v Go Ahead EaglesPSV Eindhoven 2-1 Go Ahead Eagles | Dutch Eredivisie |
| 11 | Tue 21 Oct | 56-2 v NapoliPSV Eindhoven 6-2 Napoli | UEFA Champions League Matchday 3 |
| 12 | Sun 26 Oct | 53-2 v FeyenoordFeyenoord 2-3 PSV Eindhoven | Dutch Eredivisie |
| 13 | Fri 31 Oct | 55-2 v Fortuna SittardPSV Eindhoven 5-2 Fortuna Sittard | Dutch Eredivisie |
| 14 | Tue 4 Nov | 5 1-1 v OlympiakosOlympiakos 1-1 PSV Eindhoven | UEFA Champions League Matchday 4 |
| 15 | Sun 9 Nov | 55-1 v AZ AlkmaarAZ Alkmaar 1-5 PSV Eindhoven | Dutch Eredivisie |
| 16 | Sat 22 Nov | 51-0 v NAC BredaNAC Breda 0-1 PSV Eindhoven | Dutch Eredivisie |
| 17 | Wed 26 Nov | 54-1 v LiverpoolLiverpool 1-4 PSV Eindhoven | UEFA Champions League Matchday 5 |
| 18 | Tue 9 Dec | 52-3 v Atlético MadridPSV Eindhoven 2-3 Atlético Madrid | UEFA Champions League Matchday 6 |
| 19 | Sat 13 Dec | 54-3 v Heracles AlmeloPSV Eindhoven 4-3 Heracles Almelo | Dutch Eredivisie |
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