| 1 | Sat 7 Aug 2021 | 18 1-4 v Hull CityPreston North End 1-4 Hull City | Sky Bet Championship |
| 2 | Sat 14 Aug 2021 | 181-2 v ReadingReading 2-1 Preston North End | Sky Bet Championship |
| 3 | Sat 21 Aug 2021 | 18 1-0 v Peterborough UnitedPreston North End 1-0 Peterborough United | Sky Bet Championship |
| 4 | Tue 24 Aug 2021 | 18 4-2 v MorecambeMorecambe 2-4 Preston North End | Carabao Cup Second Round |
| 5 | Sat 28 Aug 2021 | 18 3-1 v Swansea CityPreston North End 3-1 Swansea City | Sky Bet Championship |
| 6 | Sat 11 Sep 2021 | 180-0 v Bristol CityBristol City 0-0 Preston North End | Sky Bet Championship |
| 7 | Tue 14 Sep 2021 | 182-2 v Sheffield UnitedSheffield United 2-2 Preston North End | Sky Bet Championship |
| 8 | Sat 18 Sep 2021 | 181-1 v West Bromwich AlbionPreston North End 1-1 West Bromwich Albion | Sky Bet Championship |
| 9 | Sat 25 Sep 2021 | 18 0-0 v Birmingham CityBirmingham City 0-0 Preston North End | Sky Bet Championship |
| 10 | Tue 28 Sep 2021 | 181-1 v Stoke CityPreston North End 1-1 Stoke City | Sky Bet Championship |
| 11 | Sat 2 Oct 2021 | 182-3 v Queens Park RangersQueens Park Rangers 3-2 Preston North End | Sky Bet Championship |
| 12 | Sat 16 Oct 2021 | 180-0 v Derby CountyPreston North End 0-0 Derby County | Sky Bet Championship |
| 13 | Wed 27 Oct 2021 | 180-2 v LiverpoolPreston North End 0-2 Liverpool | Carabao Cup Round of 16 |
| 14 | Sat 30 Oct 2021 | 182-0 v Luton TownPreston North End 2-0 Luton Town | Sky Bet Championship |
| 15 | Sat 20 Nov 2021 | 181-2 v Cardiff CityPreston North End 1-2 Cardiff City | Sky Bet Championship |
| 16 | Sat 4 Dec 2021 | 180-1 v Blackburn RoversBlackburn Rovers 1-0 Preston North End | Sky Bet Championship |
| 17 | Sat 11 Dec 2021 | 182-1 v BarnsleyPreston North End 2-1 Barnsley | Sky Bet Championship |
| 18 | Mon 3 Jan 2022 | 18 2-1 v Stoke CityStoke City 1-2 Preston North End | Sky Bet Championship |
| 19 | Sun 9 Jan 2022 | 181-2 v Cardiff CityCardiff City 2-1 Preston North End | Emirates FA Cup Third Round |
| 20 | Sat 22 Jan 2022 | 180-1 v Swansea CitySwansea City 1-0 Preston North End | Sky Bet Championship |
| 21 | Wed 26 Jan 2022 | 182-0 v West Bromwich AlbionWest Bromwich Albion 0-2 Preston North End | Sky Bet Championship |
| 22 | Sat 29 Jan 2022 | 182-2 v Bristol CityPreston North End 2-2 Bristol City | Sky Bet Championship |
| 23 | Tue 1 Feb 2022 | 180-0 v MillwallMillwall 0-0 Preston North End | Sky Bet Championship |
| 24 | Sat 5 Feb 2022 | 181-0 v Hull CityHull City 0-1 Preston North End | Sky Bet Championship |
| 25 | Sat 12 Feb 2022 | 181-0 v Peterborough UnitedPeterborough United 0-1 Preston North End | Sky Bet Championship |
| 26 | Sat 19 Feb 2022 | 182-3 v ReadingPreston North End 2-3 Reading | Sky Bet Championship |
| 27 | Sat 26 Feb 2022 | 181-1 v Coventry CityCoventry City 1-1 Preston North End | Sky Bet Championship |
| 28 | Sat 7 May 2022 | 184-1 v MiddlesbroughPreston North End 4-1 Middlesbrough | Sky Bet Championship |
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