| 1 | Wed 26 Jan 2022 | 212-0 v West Bromwich AlbionWest Bromwich Albion 0-2 Preston North End | Sky Bet Championship |
| 2 | Sat 29 Jan 2022 | 212-2 v Bristol CityPreston North End 2-2 Bristol City | Sky Bet Championship |
| 3 | Tue 1 Feb 2022 | 210-0 v MillwallMillwall 0-0 Preston North End | Sky Bet Championship |
| 4 | Sat 5 Feb 2022 | 21 1-0 v Hull CityHull City 0-1 Preston North End | Sky Bet Championship |
| 5 | Wed 9 Feb 2022 | 210-0 v Huddersfield TownPreston North End 0-0 Huddersfield Town | Sky Bet Championship |
| 6 | Sat 12 Feb 2022 | 211-0 v Peterborough UnitedPeterborough United 0-1 Preston North End | Sky Bet Championship |
| 7 | Sat 19 Feb 2022 | 212-3 v ReadingPreston North End 2-3 Reading | Sky Bet Championship |
| 8 | Tue 22 Feb 2022 | 210-0 v Nottingham ForestPreston North End 0-0 Nottingham Forest | Sky Bet Championship |
| 9 | Sat 26 Feb 2022 | 211-1 v Coventry CityCoventry City 1-1 Preston North End | Sky Bet Championship |
| 10 | Sat 5 Mar 2022 | 212-1 v AFC BournemouthPreston North End 2-1 AFC Bournemouth | Sky Bet Championship |
| 11 | Sat 12 Mar 2022 | 210-0 v Cardiff CityCardiff City 0-0 Preston North End | Sky Bet Championship |
| 12 | Wed 16 Mar 2022 | 210-4 v Luton TownLuton Town 4-0 Preston North End | Sky Bet Championship |
| 13 | Sat 2 Apr 2022 | 210-1 v Derby CountyDerby County 1-0 Preston North End | Sky Bet Championship |
| 14 | Tue 5 Apr 2022 | 211-0 v BlackpoolPreston North End 1-0 Blackpool | Sky Bet Championship |
| 15 | Sat 9 Apr 2022 | 212-1 v Queens Park RangersPreston North End 2-1 Queens Park Rangers | Sky Bet Championship |
| 16 | Fri 15 Apr 2022 | 211-1 v MillwallPreston North End 1-1 Millwall | Sky Bet Championship |
| 17 | Tue 19 Apr 2022 | 210-3 v FulhamFulham 3-0 Preston North End | Sky Bet Championship |
| 18 | Mon 25 Apr 2022 | 211-4 v Blackburn RoversPreston North End 1-4 Blackburn Rovers | Sky Bet Championship |
| 19 | Sat 30 Apr 2022 | 213-1 v BarnsleyBarnsley 1-3 Preston North End | Sky Bet Championship |
| 20 | Sat 7 May 2022 | 214-1 v MiddlesbroughPreston North End 4-1 Middlesbrough | Sky Bet Championship |
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