| 1 | Tue 2 Sep | 22-0 v Cheltenham TownPlymouth Argyle 2-0 Cheltenham Town | EFL Trophy Southern Group B |
| 2 | Sat 6 Sep | 24-2 v Stockport CountyPlymouth Argyle 4-2 Stockport County | Sky Bet League One |
| 3 | Sat 13 Sep | 23-2 v Luton TownLuton Town 2-3 Plymouth Argyle | Sky Bet League One |
| 4 | Sat 20 Sep | 20-1 v Peterborough UnitedPlymouth Argyle 0-1 Peterborough United | Sky Bet League One |
| 5 | Sat 27 Sep | 24-0 v Burton AlbionBurton Albion 0-4 Plymouth Argyle | Sky Bet League One |
| 6 | Sat 4 Oct | 21-1 v Wigan AthleticPlymouth Argyle 1-1 Wigan Athletic | Sky Bet League One |
| 7 | Sat 18 Oct | 21-2 v AFC WimbledonPlymouth Argyle 1-2 AFC Wimbledon | Sky Bet League One |
| 8 | Thu 23 Oct | 20-2 v Exeter CityExeter City 2-0 Plymouth Argyle | Sky Bet League One |
| 9 | Tue 28 Oct | 20-2 v Mansfield TownMansfield Town 2-0 Plymouth Argyle | Sky Bet League One |
| 10 | Sat 1 Nov | 2 0-2 v Wycombe WanderersWycombe Wanderers 2-0 Plymouth Argyle | Emirates FA Cup First Round |
| 11 | Sat 8 Nov | 2 1-3 v Huddersfield TownHuddersfield Town 3-1 Plymouth Argyle | Sky Bet League One |
| 12 | Tue 11 Nov | 2 0-1 v Bristol RoversBristol Rovers 1-0 Plymouth Argyle | EFL Trophy Southern Group B |
| 13 | Sat 22 Nov | 21-0 v Port ValePort Vale 0-1 Plymouth Argyle | Sky Bet League One |
| 14 | Sat 29 Nov | 2 0-3 v Northampton TownPlymouth Argyle 0-3 Northampton Town | Sky Bet League One |
| 15 | Tue 2 Dec | 21-0 v Leyton OrientLeyton Orient 0-1 Plymouth Argyle | EFL Trophy Round of 32 |
| 16 | Sat 6 Dec | 20-1 v Bradford CityPlymouth Argyle 0-1 Bradford City | Sky Bet League One |
| 17 | Tue 9 Dec | 21-0 v Wycombe WanderersWycombe Wanderers 0-1 Plymouth Argyle | Sky Bet League One |
| 18 | Sat 13 Dec | 21-0 v Rotherham UnitedPlymouth Argyle 1-0 Rotherham United | Sky Bet League One |
| 19 | Sat 20 Dec | 25-1 v Doncaster RoversDoncaster Rovers 1-5 Plymouth Argyle | Sky Bet League One |
| 20 | Fri 26 Dec | 21-4 v ReadingPlymouth Argyle 1-4 Reading | Sky Bet League One |
| 21 | Mon 29 Dec | 21-1 v Wycombe WanderersPlymouth Argyle 1-1 Wycombe Wanderers | Sky Bet League One |
| 22 | Thu 1 Jan | 21-1 v StevenageStevenage 1-1 Plymouth Argyle | Sky Bet League One |
| 23 | Sun 4 Jan | 23-0 v Burton AlbionPlymouth Argyle 3-0 Burton Albion | Sky Bet League One |
| 24 | Tue 13 Jan | 24-3 v Bristol RoversBristol Rovers 3-4 Plymouth Argyle | EFL Trophy Round of 16 |
| 25 | Sat 17 Jan | 2 1-0 v Peterborough UnitedPeterborough United 0-1 Plymouth Argyle | Sky Bet League One |
| 26 | Sat 24 Jan | 2 1-0 v Luton TownPlymouth Argyle 1-0 Luton Town | Sky Bet League One |
| 27 | Tue 27 Jan | 21-1 v Mansfield TownPlymouth Argyle 1-1 Mansfield Town | Sky Bet League One |
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