| 1 | Tue 10 Aug 2021 | 22 4-0 v Peterborough UnitedPeterborough United 0-4 Plymouth Argyle | Carabao Cup First Round |
| 2 | Sat 14 Aug 2021 | 221-0 v GillinghamPlymouth Argyle 1-0 Gillingham | Sky Bet League One |
| 3 | Sat 21 Aug 2021 | 223-0 v Shrewsbury TownShrewsbury Town 0-3 Plymouth Argyle | Sky Bet League One |
| 4 | Sat 28 Aug 2021 | 221-1 v Fleetwood TownPlymouth Argyle 1-1 Fleetwood Town | Sky Bet League One |
| 5 | Sat 11 Sep 2021 | 223-0 v Sheffield WednesdayPlymouth Argyle 3-0 Sheffield Wednesday | Sky Bet League One |
| 6 | Sat 18 Sep 2021 | 221-0 v AFC WimbledonAFC Wimbledon 0-1 Plymouth Argyle | Sky Bet League One |
| 7 | Tue 21 Sep 2021 | 222-2 v PortsmouthPortsmouth 2-2 Plymouth Argyle | Sky Bet League One |
| 8 | Sat 25 Sep 2021 | 22 2-1 v Doncaster RoversPlymouth Argyle 2-1 Doncaster Rovers | Sky Bet League One |
| 9 | Tue 28 Sep 2021 | 22 1-1 v Crewe AlexandraPlymouth Argyle 1-1 Crewe Alexandra | Sky Bet League One |
| 10 | Sat 2 Oct 2021 | 222-2 v Lincoln CityLincoln City 2-2 Plymouth Argyle | Sky Bet League One |
| 11 | Sat 16 Oct 2021 | 223-1 v Oxford UnitedOxford United 1-3 Plymouth Argyle | Sky Bet League One |
| 12 | Tue 19 Oct 2021 | 22 3-0 v Bolton WanderersPlymouth Argyle 3-0 Bolton Wanderers | Sky Bet League One |
| 13 | Sat 23 Oct 2021 | 22 1-1 v MorecambeMorecambe 1-1 Plymouth Argyle | Sky Bet League One |
| 14 | Sat 30 Oct 2021 | 222-1 v Ipswich TownPlymouth Argyle 2-1 Ipswich Town | Sky Bet League One |
| 15 | Sun 7 Nov 2021 | 220-0 v Sheffield WednesdaySheffield Wednesday 0-0 Plymouth Argyle | Emirates FA Cup First Round |
| 16 | Tue 23 Nov 2021 | 220-3 v Wycombe WanderersPlymouth Argyle 0-3 Wycombe Wanderers | Sky Bet League One |
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