| 1 | Sat 9 Aug | 40-1 v PortsmouthOxford United 0-1 Portsmouth | Sky Bet Championship |
| 2 | Sun 17 Aug | 42-3 v Hull CityHull City 3-2 Oxford United | Sky Bet Championship |
| 3 | Sat 23 Aug | 40-1 v Birmingham CityBirmingham City 1-0 Oxford United | Sky Bet Championship |
| 4 | Wed 27 Aug | 40-6 v Brighton & Hove AlbionOxford United 0-6 Brighton & Hove Albion | Carabao Cup Second Round |
| 5 | Sat 30 Aug | 42-2 v Coventry CityOxford United 2-2 Coventry City | Sky Bet Championship |
| 6 | Sun 21 Sep | 4 3-1 v Bristol CityBristol City 1-3 Oxford United | Sky Bet Championship |
| 7 | Sat 27 Sep | 4 0-1 v Sheffield UnitedOxford United 0-1 Sheffield United | Sky Bet Championship |
| 8 | Sat 4 Oct | 41-2 v WatfordWatford 2-1 Oxford United | Sky Bet Championship |
| 9 | Sat 18 Oct | 4 1-0 v Derby CountyOxford United 1-0 Derby County | Sky Bet Championship |
| 10 | Wed 22 Oct | 40-1 v WrexhamWrexham 1-0 Oxford United | Sky Bet Championship |
| 11 | Sat 25 Oct | 42-1 v Sheffield WednesdaySheffield Wednesday 1-2 Oxford United | Sky Bet Championship |
| 12 | Sat 1 Nov | 42-2 v MillwallOxford United 2-2 Millwall | Sky Bet Championship |
| 13 | Tue 4 Nov | 40-3 v Stoke CityOxford United 0-3 Stoke City | Sky Bet Championship |
| 14 | Sat 8 Nov | 41-2 v West Bromwich AlbionWest Bromwich Albion 2-1 Oxford United | Sky Bet Championship |
| 15 | Sat 22 Nov | 41-1 v MiddlesbroughOxford United 1-1 Middlesbrough | Sky Bet Championship |
| 16 | Tue 25 Nov | 41-1 v Norwich CityNorwich City 1-1 Oxford United | Sky Bet Championship |
| 17 | Fri 28 Nov | 42-1 v Ipswich TownOxford United 2-1 Ipswich Town | Sky Bet Championship |
| 18 | Sat 6 Dec | 40-2 v Swansea CitySwansea City 2-0 Oxford United | Sky Bet Championship |
| 19 | Tue 9 Dec | 41-1 v Blackburn RoversBlackburn Rovers 1-1 Oxford United | Sky Bet Championship |
| 20 | Sat 13 Dec | 4 1-2 v Preston North EndOxford United 1-2 Preston North End | Sky Bet Championship |
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