| 1 | Wed 11 Jul 2018 | 12-0 v UCDUCD 0-2 Oxford United | Friendly |
| 2 | Fri 27 Jul 2018 | 10-1 v Milton Keynes DonsMilton Keynes Dons 1-0 Oxford United | Friendly |
| 3 | Sat 4 Aug 2018 | 10-4 v BarnsleyBarnsley 4-0 Oxford United | Sky Bet League One |
| 4 | Sat 11 Aug 2018 | 10-2 v Fleetwood TownOxford United 0-2 Fleetwood Town | Sky Bet League One |
| 5 | Tue 9 Oct 2018 | 11-2 v Northampton TownOxford United 1-2 Northampton Town | Checkatrade Trophy Southern Group F |
| 6 | Sat 13 Oct 2018 | 12-0 v Plymouth ArgyleOxford United 2-0 Plymouth Argyle | Sky Bet League One |
| 7 | Sat 20 Oct 2018 | 10-0 v Bristol RoversBristol Rovers 0-0 Oxford United | Sky Bet League One |
| 8 | Tue 23 Oct 2018 | 11-1 v Charlton AthleticCharlton Athletic 1-1 Oxford United | Sky Bet League One |
| 9 | Sat 27 Oct 2018 | 13-0 v Shrewsbury TownOxford United 3-0 Shrewsbury Town | Sky Bet League One |
| 10 | Sat 3 Nov 2018 | 13-3 v Scunthorpe UnitedScunthorpe United 3-3 Oxford United | Sky Bet League One |
| 11 | Tue 6 Nov 2018 | 13-0 v Wycombe WanderersWycombe Wanderers 0-3 Oxford United | Checkatrade Trophy Southern Group F |
| 12 | Sat 10 Nov 2018 | 10-0 v Forest Green RoversOxford United 0-0 Forest Green Rovers | Emirates FA Cup First Round |
| 13 | Sat 17 Nov 2018 | 11-0 v GillinghamOxford United 1-0 Gillingham | Sky Bet League One |
| 14 | Tue 20 Nov 2018 | 13-0 v Forest Green RoversForest Green Rovers 0-3 Oxford United | Emirates FA Cup First Round Replay |
| 15 | Tue 27 Nov 2018 | 14-2 v RochdaleOxford United 4-2 Rochdale | Sky Bet League One |
| 16 | Sat 1 Dec 2018 | 12-1 v Plymouth ArgylePlymouth Argyle 1-2 Oxford United | Emirates FA Cup Second Round |
| 17 | Sat 8 Dec 2018 | 12-2 v Peterborough UnitedPeterborough United 2-2 Oxford United | Sky Bet League One |
| 18 | Sat 15 Dec 2018 | 12-0 v BlackpoolOxford United 2-0 Blackpool | Sky Bet League One |
| 19 | Sat 22 Dec 2018 | 12-2 v Doncaster RoversDoncaster Rovers 2-2 Oxford United | Sky Bet League One |
| 20 | Wed 26 Dec 2018 | 10-1 v Southend UnitedOxford United 0-1 Southend United | Sky Bet League One |
| 21 | Sat 29 Dec 2018 | 10-2 v Bristol RoversOxford United 0-2 Bristol Rovers | Sky Bet League One |
| 22 | Tue 1 Jan 2019 | 10-3 v Plymouth ArgylePlymouth Argyle 3-0 Oxford United | Sky Bet League One |
| 23 | Tue 8 Jan 2019 | 11-1 v Cheltenham TownCheltenham Town 1-1 Oxford United | Checkatrade Trophy Second Round |
| 24 | Sat 12 Jan 2019 | 12-2 v Fleetwood TownFleetwood Town 2-2 Oxford United | Sky Bet League One |
| 25 | Sat 19 Jan 2019 | 12-1 v PortsmouthOxford United 2-1 Portsmouth | Sky Bet League One |
| 26 | Tue 22 Jan 2019 | 12-5 v BuryBury 5-2 Oxford United | Checkatrade Trophy Fourth Round |
| 27 | Tue 29 Jan 2019 | 12-2 v BarnsleyOxford United 2-2 Barnsley | Sky Bet League One |
| 28 | Sat 2 Feb 2019 | 10-0 v Burton AlbionBurton Albion 0-0 Oxford United | Sky Bet League One |
| 29 | Sat 9 Feb 2019 | 11-1 v SunderlandOxford United 1-1 Sunderland | Sky Bet League One |
| 30 | Sat 16 Feb 2019 | 10-1 v Peterborough UnitedOxford United 0-1 Peterborough United | Sky Bet League One |
| 31 | Tue 19 Feb 2019 | 12-4 v Accrington StanleyAccrington Stanley 4-2 Oxford United | Sky Bet League One |
| 32 | Sat 23 Feb 2019 | 11-0 v BlackpoolBlackpool 0-1 Oxford United | Sky Bet League One |
| 33 | Sat 2 Mar 2019 | 12-1 v Scunthorpe UnitedOxford United 2-1 Scunthorpe United | Sky Bet League One |
| 34 | Sat 9 Mar 2019 | 10-1 v GillinghamGillingham 1-0 Oxford United | Sky Bet League One |
| 35 | Tue 12 Mar 2019 | 10-0 v RochdaleRochdale 0-0 Oxford United | Sky Bet League One |
| 36 | Sat 16 Mar 2019 | 11-0 v Bradford CityOxford United 1-0 Bradford City | Sky Bet League One |
| 37 | Sat 23 Mar 2019 | 11-0 v Coventry CityCoventry City 0-1 Oxford United | Sky Bet League One |
| 38 | Sat 30 Mar 2019 | 12-1 v Wycombe WanderersOxford United 2-1 Wycombe Wanderers | Sky Bet League One |
| 39 | Sat 6 Apr 2019 | 13-1 v WalsallWalsall 1-3 Oxford United | Sky Bet League One |
| 40 | Sat 13 Apr 2019 | 10-0 v AFC WimbledonOxford United 0-0 AFC Wimbledon | Sky Bet League One |
| 41 | Fri 19 Apr 2019 | 1 2-1 v Charlton AthleticOxford United 2-1 Charlton Athletic | Sky Bet League One |
| 42 | Sat 27 Apr 2019 | 12-2 v Doncaster RoversOxford United 2-2 Doncaster Rovers | Sky Bet League One |
| 43 | Sat 4 May 2019 | 11-3 v Luton TownLuton Town 3-1 Oxford United | Sky Bet League One |
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