| 1 | Tue 14 Aug 2012 | 10-0 v BournemouthOxford United 0-0 Bournemouth | Capital One Cup First Round |
| 2 | Sat 18 Aug 2012 | 12-0 v Bristol RoversBristol Rovers 0-2 Oxford United | npower League Two |
| 3 | Tue 21 Aug 2012 | 12-0 v Southend UnitedOxford United 2-0 Southend United | npower League Two |
| 4 | Sat 25 Aug 2012 | 12-1 v Plymouth ArgyleOxford United 2-1 Plymouth Argyle | npower League Two |
| 5 | Tue 28 Aug 2012 | 10-3 v Leeds UnitedLeeds United 3-0 Oxford United | Capital One Cup Second Round |
| 6 | Sat 1 Sep 2012 | 11-3 v York CityYork City 3-1 Oxford United | npower League Two |
| 7 | Wed 5 Sep 2012 | 11-0 v Swindon TownOxford United 1-0 Swindon Town | Johnstone's Paint Trophy First Round |
| 8 | Sat 8 Sep 2012 | 12-4 v Exeter CityOxford United 2-4 Exeter City | npower League Two |
| 9 | Sat 15 Sep 2012 | 10-4 v Burton AlbionBurton Albion 4-0 Oxford United | npower League Two |
| 10 | Tue 18 Sep 2012 | 11-2 v Cheltenham TownCheltenham Town 2-1 Oxford United | npower League Two |
| 11 | Sat 22 Sep 2012 | 10-2 v Bradford CityOxford United 0-2 Bradford City | npower League Two |
| 12 | Tue 2 Oct 2012 | 13-2 v AFC WimbledonOxford United 3-2 AFC Wimbledon | npower League Two |
| 13 | Sat 6 Oct 2012 | 10-0 v GillinghamOxford United 0-0 Gillingham | npower League Two |
| 14 | Tue 9 Oct 2012 | 14-2 v Cheltenham TownCheltenham Town 2-4 Oxford United | Johnstone's Paint Trophy Second Round |
| 15 | Mon 15 Oct 2012 | 10-3 v Port ValePort Vale 3-0 Oxford United | npower League Two |
| 16 | Sat 20 Oct 2012 | 15-0 v Accrington StanleyOxford United 5-0 Accrington Stanley | npower League Two |
| 17 | Tue 23 Oct 2012 | 10-2 v RochdaleRochdale 2-0 Oxford United | npower League Two |
| 18 | Sat 27 Oct 2012 | 13-1 v Wycombe WanderersWycombe Wanderers 1-3 Oxford United | npower League Two |
| 19 | Sat 3 Nov 2012 | 12-0 v BarnetBarnet 0-2 Oxford United | FA Cup with Budweiser First Round |
| 20 | Tue 6 Nov 2012 | 12-3 v Dagenham & RedbridgeOxford United 2-3 Dagenham & Redbridge | npower League Two |
| 21 | Sat 10 Nov 2012 | 10-0 v Torquay UnitedOxford United 0-0 Torquay United | npower League Two |
| 22 | Sat 17 Nov 2012 | 11-2 v ChesterfieldChesterfield 2-1 Oxford United | npower League Two |
| 23 | Tue 20 Nov 2012 | 12-2 v BarnetBarnet 2-2 Oxford United | npower League Two |
| 24 | Sat 24 Nov 2012 | 12-1 v Northampton TownOxford United 2-1 Northampton Town | npower League Two |
| 25 | Sat 1 Dec 2012 | 13-3 v Accrington StanleyAccrington Stanley 3-3 Oxford United | FA Cup with Budweiser Second Round |
| 26 | Tue 4 Dec 2012 | 11-1 v Plymouth ArgylePlymouth Argyle 1-1 Oxford United | Johnstone's Paint Trophy Southern Area Quarter Final |
| 27 | Sat 8 Dec 2012 | 11-1 v Aldershot TownOxford United 1-1 Aldershot Town | npower League Two |
| 28 | Sat 15 Dec 2012 | 11-1 v MorecambeMorecambe 1-1 Oxford United | npower League Two |
| 29 | Tue 18 Dec 2012 | 12-0 v Accrington StanleyOxford United 2-0 Accrington Stanley | FA Cup with Budweiser Second Round Replay |
| 30 | Wed 26 Dec 2012 | 13-1 v Exeter CityExeter City 1-3 Oxford United | npower League Two |
| 31 | Sat 29 Dec 2012 | 13-0 v AFC WimbledonAFC Wimbledon 0-3 Oxford United | npower League Two |
| 32 | Tue 1 Jan 2013 | 11-0 v Cheltenham TownOxford United 1-0 Cheltenham Town | npower League Two |
| 33 | Sat 5 Jan 2013 | 10-3 v Sheffield UnitedOxford United 0-3 Sheffield United | FA Cup with Budweiser Third Round |
| 34 | Tue 8 Jan 2013 | 13-3 v Southend UnitedOxford United 3-3 Southend United | Johnstone's Paint Trophy Southern Area Semi Final |
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