| 1 | Sun 12 Sep 2021 | 32-1 v KV KortrijkOud-Heverlee Leuven 2-1 KV Kortrijk | Belgian First Division A |
| 2 | Sat 18 Sep 2021 | 3 0-2 v MechelenMechelen 2-0 Oud-Heverlee Leuven | Belgian First Division A |
| 3 | Sat 16 Oct 2021 | 32-2 v Standard LiègeStandard Liège 2-2 Oud-Heverlee Leuven | Belgian First Division A |
| 4 | Sun 24 Oct 2021 | 34-1 v Sint-Truidense VVOud-Heverlee Leuven 4-1 Sint-Truidense VV | Belgian First Division A |
| 5 | Sun 31 Oct 2021 | 32-2 v RSC AnderlechtRSC Anderlecht 2-2 Oud-Heverlee Leuven | Belgian First Division A |
| 6 | Fri 5 Nov 2021 | 31-0 v KV OostendeOud-Heverlee Leuven 1-0 KV Oostende | Belgian First Division A |
| 7 | Sat 4 Dec 2021 | 30-1 v KAA GentOud-Heverlee Leuven 0-1 KAA Gent | Belgian First Division A |
| 8 | Sat 11 Dec 2021 | 31-2 v KV KortrijkKV Kortrijk 2-1 Oud-Heverlee Leuven | Belgian First Division A |
| 9 | Wed 15 Dec 2021 | 31-4 v Club BruggeOud-Heverlee Leuven 1-4 Club Brugge | Belgian First Division A |
| 10 | Sun 19 Dec 2021 | 32-1 v Standard LiègeOud-Heverlee Leuven 2-1 Standard Liège | Belgian First Division A |
| 11 | Mon 27 Dec 2021 | 33-0 v Sporting de CharleroiSporting de Charleroi 0-3 Oud-Heverlee Leuven | Belgian First Division A |
| 12 | Sat 5 Feb 2022 | 33-1 v KV OostendeKV Oostende 1-3 Oud-Heverlee Leuven | Belgian First Division A |
| 13 | Wed 9 Feb 2022 | 32-1 v KRC GenkOud-Heverlee Leuven 2-1 KRC Genk | Belgian First Division A |
| 14 | Sat 26 Feb 2022 | 30-0 v RSC AnderlechtOud-Heverlee Leuven 0-0 RSC Anderlecht | Belgian First Division A |
| 15 | Sun 6 Mar 2022 | 31-3 v KAS EupenKAS Eupen 3-1 Oud-Heverlee Leuven | Belgian First Division A |
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