| 1 | Sat 31 Jul 2021 | 41-1 v Cercle BruggeCercle Brugge 1-1 Oud-Heverlee Leuven | Belgian First Division A |
| 2 | Sun 8 Aug 2021 | 41-1 v Sporting de CharleroiOud-Heverlee Leuven 1-1 Sporting de Charleroi | Belgian First Division A |
| 3 | Sun 29 Aug 2021 | 42-2 v Royal AntwerpRoyal Antwerp 2-2 Oud-Heverlee Leuven | Belgian First Division A |
| 4 | Sun 12 Sep 2021 | 42-1 v KV KortrijkOud-Heverlee Leuven 2-1 KV Kortrijk | Belgian First Division A |
| 5 | Sat 18 Sep 2021 | 40-2 v MechelenMechelen 2-0 Oud-Heverlee Leuven | Belgian First Division A |
| 6 | Fri 24 Sep 2021 | 4 1-1 v Club BruggeClub Brugge 1-1 Oud-Heverlee Leuven | Belgian First Division A |
| 7 | Sat 2 Oct 2021 | 4 0-0 v Germinal BeerschotOud-Heverlee Leuven 0-0 Germinal Beerschot | Belgian First Division A |
| 8 | Sat 4 Dec 2021 | 4 0-1 v KAA GentOud-Heverlee Leuven 0-1 KAA Gent | Belgian First Division A |
| 9 | Sat 11 Dec 2021 | 41-2 v KV KortrijkKV Kortrijk 2-1 Oud-Heverlee Leuven | Belgian First Division A |
| 10 | Wed 15 Dec 2021 | 41-4 v Club BruggeOud-Heverlee Leuven 1-4 Club Brugge | Belgian First Division A |
| 11 | Sun 19 Dec 2021 | 42-1 v Standard LiègeOud-Heverlee Leuven 2-1 Standard Liège | Belgian First Division A |
| 12 | Mon 27 Dec 2021 | 43-0 v Sporting de CharleroiSporting de Charleroi 0-3 Oud-Heverlee Leuven | Belgian First Division A |
| 13 | Sat 12 Feb 2022 | 43-2 v Cercle BruggeOud-Heverlee Leuven 3-2 Cercle Brugge | Belgian First Division A |
| 14 | Sun 20 Feb 2022 | 4 0-2 v Sint-Truidense VVSint-Truidense VV 2-0 Oud-Heverlee Leuven | Belgian First Division A |
| 15 | Sat 19 Mar 2022 | 41-1 v SeraingSeraing 1-1 Oud-Heverlee Leuven | Belgian First Division A |
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