| 1 | Sat 16 Aug | 441-0 v LensLens 0-1 Olympique Lyonnais | French Ligue 1 |
| 2 | Sat 23 Aug | 443-0 v MetzOlympique Lyonnais 3-0 Metz | French Ligue 1 |
| 3 | Sun 31 Aug | 441-0 v Olympique MarseilleOlympique Lyonnais 1-0 Olympique Marseille | French Ligue 1 |
| 4 | Sun 14 Sep | 441-3 v RennesRennes 3-1 Olympique Lyonnais | French Ligue 1 |
| 5 | Fri 19 Sep | 44 1-0 v AngersOlympique Lyonnais 1-0 Angers | French Ligue 1 |
| 6 | Thu 25 Sep | 441-0 v FC UtrechtFC Utrecht 0-1 Olympique Lyonnais | UEFA Europa League Matchday 1 |
| 7 | Sun 28 Sep | 441-0 v LilleLille 0-1 Olympique Lyonnais | French Ligue 1 |
| 8 | Thu 2 Oct | 442-0 v SV Red Bull SalzburgOlympique Lyonnais 2-0 SV Red Bull Salzburg | UEFA Europa League Matchday 2 |
| 9 | Thu 23 Oct | 442-0 v BaselOlympique Lyonnais 2-0 Basel | UEFA Europa League Matchday 3 |
| 10 | Thu 6 Nov | 440-2 v Real BetisReal Betis 2-0 Olympique Lyonnais | UEFA Europa League Matchday 4 |
| 11 | Sun 9 Nov | 442-3 v Paris St GermainOlympique Lyonnais 2-3 Paris St Germain | French Ligue 1 |
| 12 | Sun 23 Nov | 44 0-0 v AuxerreAuxerre 0-0 Olympique Lyonnais | French Ligue 1 |
| 13 | Thu 27 Nov | 446-0 v Maccabi Tel-AvivMaccabi Tel-Aviv 0-6 Olympique Lyonnais | UEFA Europa League Matchday 5 |
| 14 | Sun 30 Nov | 443-0 v NantesOlympique Lyonnais 3-0 Nantes | French Ligue 1 |
| 15 | Thu 11 Dec | 442-1 v Go Ahead EaglesOlympique Lyonnais 2-1 Go Ahead Eagles | UEFA Europa League Matchday 6 |
| 16 | Sun 14 Dec | 441-0 v Le HavreOlympique Lyonnais 1-0 Le Havre | French Ligue 1 |
| 17 | Sat 3 Jan | 443-1 v MonacoMonaco 1-3 Olympique Lyonnais | French Ligue 1 |
| 18 | Sun 18 Jan | 442-1 v BrestOlympique Lyonnais 2-1 Brest | French Ligue 1 |
| 19 | Thu 22 Jan | 441-0 v Young BoysYoung Boys 0-1 Olympique Lyonnais | UEFA Europa League Matchday 7 |
| 20 | Sun 25 Jan | 445-2 v MetzMetz 2-5 Olympique Lyonnais | French Ligue 1 |
| 21 | Thu 29 Jan | 444-2 v PAOK FCOlympique Lyonnais 4-2 PAOK FC | UEFA Europa League Matchday 8 |
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