| 1 | Sat 16 Aug | 16 1-0 v LensLens 0-1 Olympique Lyonnais | French Ligue 1 |
| 2 | Sat 23 Aug | 163-0 v MetzOlympique Lyonnais 3-0 Metz | French Ligue 1 |
| 3 | Sun 31 Aug | 16 1-0 v Olympique MarseilleOlympique Lyonnais 1-0 Olympique Marseille | French Ligue 1 |
| 4 | Sun 14 Sep | 161-3 v RennesRennes 3-1 Olympique Lyonnais | French Ligue 1 |
| 5 | Sat 18 Oct | 162-3 v NiceNice 3-2 Olympique Lyonnais | French Ligue 1 |
| 6 | Thu 23 Oct | 162-0 v BaselOlympique Lyonnais 2-0 Basel | UEFA Europa League Matchday 3 |
| 7 | Wed 29 Oct | 16 3-3 v Paris FCParis FC 3-3 Olympique Lyonnais | French Ligue 1 |
| 8 | Thu 6 Nov | 16 0-2 v Real BetisReal Betis 2-0 Olympique Lyonnais | UEFA Europa League Matchday 4 |
| 9 | Sun 23 Nov | 160-0 v AuxerreAuxerre 0-0 Olympique Lyonnais | French Ligue 1 |
| 10 | Thu 27 Nov | 166-0 v Maccabi Tel-AvivMaccabi Tel-Aviv 0-6 Olympique Lyonnais | UEFA Europa League Matchday 5 |
| 11 | Sun 30 Nov | 163-0 v NantesOlympique Lyonnais 3-0 Nantes | French Ligue 1 |
| 12 | Sun 7 Dec | 160-1 v LorientLorient 1-0 Olympique Lyonnais | French Ligue 1 |
| 13 | Sun 14 Dec | 161-0 v Le HavreOlympique Lyonnais 1-0 Le Havre | French Ligue 1 |
| 14 | Sat 3 Jan | 163-1 v MonacoMonaco 1-3 Olympique Lyonnais | French Ligue 1 |
| 15 | Sun 18 Jan | 16 2-1 v BrestOlympique Lyonnais 2-1 Brest | French Ligue 1 |
| 16 | Thu 29 Jan | 164-2 v PAOK FCOlympique Lyonnais 4-2 PAOK FC | UEFA Europa League Matchday 8 |
| 17 | Sun 1 Feb | 161-0 v LilleOlympique Lyonnais 1-0 Lille | French Ligue 1 |
| 18 | Sat 7 Feb | 161-0 v NantesNantes 0-1 Olympique Lyonnais | French Ligue 1 |
| 19 | Sun 15 Feb | 16 2-0 v NiceOlympique Lyonnais 2-0 Nice | French Ligue 1 |
| 20 | Sun 22 Feb | 161-3 v StrasbourgStrasbourg 3-1 Olympique Lyonnais | French Ligue 1 |
| 21 | Sun 1 Mar | 162-3 v Olympique MarseilleOlympique Marseille 3-2 Olympique Lyonnais | French Ligue 1 |
| 22 | Sun 8 Mar | 161-1 v Paris FCOlympique Lyonnais 1-1 Paris FC | French Ligue 1 |
| 23 | Thu 12 Mar | 161-1 v Celta VigoCelta Vigo 1-1 Olympique Lyonnais | UEFA Europa League Round of 16 |
| 24 | Sun 15 Mar | 160-0 v Le HavreLe Havre 0-0 Olympique Lyonnais | French Ligue 1 |
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