| 1 | Thu 8 Aug | 31-1 v Hapoel Be-er ShevaMladá Boleslav 1-1 Hapoel Be-er Sheva | UEFA Europa Conference League Third Qualifying Round |
| 2 | Thu 15 Aug | 34-2 v Hapoel Be-er ShevaHapoel Be-er Sheva 2-4 Mladá Boleslav | UEFA Europa Conference League Third Qualifying Round |
| 3 | Thu 22 Aug | 32-2 v PaksMladá Boleslav 2-2 Paks | UEFA Europa Conference League Play-off |
| 4 | Thu 29 Aug | 33-0 v PaksPaks 0-3 Mladá Boleslav | UEFA Europa Conference League Play-off |
| 5 | Thu 3 Oct | 30-2 v NoahNoah 2-0 Mladá Boleslav | UEFA Europa Conference League Matchday 1 |
| 6 | Thu 24 Oct | 30-1 v LuganoMladá Boleslav 0-1 Lugano | UEFA Europa Conference League Matchday 2 |
| 7 | Thu 7 Nov | 31-2 v Vitória GuimarãesVitória Guimarães 2-1 Mladá Boleslav | UEFA Europa Conference League Matchday 3 |
| 8 | Thu 28 Nov | 32-1 v Real BetisMladá Boleslav 2-1 Real Betis | UEFA Europa Conference League Matchday 4 |
| 9 | Thu 12 Dec | 31-0 v Jagiellonia BiałystokMladá Boleslav 1-0 Jagiellonia Białystok | UEFA Europa Conference League Matchday 5 |
| 10 | Thu 19 Dec | 33-4 v MoldeMolde 4-3 Mladá Boleslav | UEFA Europa Conference League Matchday 6 |
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